Omaha, NENCT06046495Now EnrollingIRB Ready

Non-Small Cell Lung Cancer Clinical Trial in Omaha, NE

Access cutting-edge non-small cell lung cancer treatment through this clinical trial at a research site in Omaha. Study-provided care at no cost to qualified participants.

Sponsored by Avistone Biotechnology Co., Ltd.

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Expert Care in Omaha

Access non-small cell lung cancer specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related non-small cell lung cancer treatment provided free

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Check if you qualify for this non-small cell lung cancer clinical trial in Omaha, NE

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Omaha

    Convenient for NE residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Omaha site if eligible
  4. 4Begin participation

About This Non-Small Cell Lung Cancer Study in Omaha

This is a Phase I, multicenter, open-label, dose escalation and dose expansion study to assess the safety and pharmacokinetic profile of PLB1004, a mono-anilino-pyrimidine compound, given alone in NSCLC patients with EGFR exon 20 insertion mutations,uncommon mutations, classical mutations (Ex19del and L858R), and drug-resistant mutation (T790M). Patients will be enrolled and dosed according to the most current protocol. This study is made of two Parts. Part 1 includes a dose escalation into 7 cohorts and patient allocation to these cohorts will be via slot allocation. Each cohort has a minimum of 3 and a maximum of 6 patients for a total of 21 - 42 patients. The patient population of the dose escalation phase will include patients with advanced NSCLC harboring EGFR classical mutations or Ex20ins mutations, or uncommon mutations. Part 2 includes an expansion phase and the expansion phase will explore one or more dose levels of PLB1004 in NSCLC patients with EGFR Ex20ins mutations, classical mutations, or uncommon mutations.

Sponsor: Avistone Biotechnology Co., Ltd.

Who Can Participate

Inclusion Criteria

Ability to understand and willingness to sign a written informed consent document;
Male or female adult patients 18 years of age or older;
Patients should have recovered from toxicities related to prior anti-tumor therapy;
Patients should have recovered from the effects of major surgery;
Have a documented EGFR mutation by a local test in tissue or plasma;
At least 12 weeks life expectancy;
Must have at least one measurable lesion per RECIST v 1.1;
Sexually active males and females of childbearing potential must agree to take effective contraceptive measures.

Exclusion Criteria

Received radiotherapy within 14 days before enrollment;
Have significant or uncontrolled systemic disease;
Have significant or uncontrolled cardiovascular disease;
Have had other diagnosed malignant diseases that required treatment within the past 3 years besides NSCLC;
Currently have or had a history of interstitial lung disease, drug-induced interstitial lung disease, or radiation pneumonia that requires steroid therapy;
Have known hypersensitivity to the similar drugs and excipients of PLB1004;
Pregnant or lactating women;
Have used other experimental drugs within 2 weeks prior to the first dose of PLB1004;
Have any condition or illness that could affect the compliance with the protocol.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Omaha?

Yes, this clinical trial (NCT06046495) has an active research site in Omaha, NE that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Non-Small Cell Lung Cancer Treatment Options in Omaha, NE

If you're searching for non-small cell lung cancer treatment options in Omaha, NE, this clinical trial (NCT06046495) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Omaha research site is actively enrolling participants for this clinical trial. You'll receive care from experienced non-small cell lung cancer specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all non-small cell lung cancer clinical trials near you to find additional studies recruiting in your area.

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