Denver, CONCT07519655Now EnrollingIRB Ready

Non-Small-Cell Lung Clinical Trial in Denver, CO

Access cutting-edge non-small-cell lung treatment through this clinical trial at a research site in Denver. Study-provided care at no cost to qualified participants.

Sponsored by Pfizer

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Expert Care in Denver

Access non-small-cell lung specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related non-small-cell lung treatment provided free

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Check if you qualify for this non-small-cell lung clinical trial in Denver, CO

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Why Participate?

  • No-Cost Study Care

  • Local to Denver

    Convenient for CO residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Denver site if eligible
  4. 4Begin participation

About This Non-Small-Cell Lung Study in Denver

This is an early-stage (Phase 1) clinical study testing a new study medicine called PF-08046033. The goal of the study is to understand how safe the medicine is, how well people tolerate it, how it behaves in the body, and whether it shows early signs of helping to treat cancer. The study includes adult participants who have advanced cancers that cannot be removed by surgery or have spread to other parts of the body. These cancers include non-small cell lung cancer, esophageal squamous cell cancer, and melanoma. The study has two parts: In the first part, small groups of participants receive increasing doses of the study medicine. This helps researchers find a dose that is safe and suitable for further testing. Once a suitable dose is identified, the second part enrolls more participants with specific cancer types to better understand the safety of the medicine and whether it shows signs of helping control the cancer. Participants receive the study medicine through regular treatment cycles and are closely monitored for side effects and how their cancer responds. The information from this study will help researchers decide whether PF-08046033 should be studied further in later-stage clinical trials.

Sponsor: Pfizer

Who Can Participate

Inclusion Criteria

Participants must have histologically-confirmed metastatic or unresectable locally advanced NSCLC, ESCC, or cutaneous melanoma.
Participants must have disease that has progressed on or be unable to tolerate standard treatments (Part 1) or 1-2 prior systemic therapies (Part 2).
Participants must have measurable disease.
Eastern Cooperative Oncology Group (ECOG) performance status is 0-1.

Exclusion Criteria

Participants with known clinically active central nervous system (CNS) metastases.
Participants with pre-existing neuropathy ≥Grade 2 per NCI CTCAE v 5.0.
Uncontrolled diabetes mellitus with hemoglobin (Hgb) A1C ≥10.0%.
Untreated clinically significant thromboembolic disease.
Previous exposure to GPNMB-targeted therapy.
Known or suspected hypersensitivity to any component or excipient contained in the drug formulation of study intervention.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Denver?

Yes, this clinical trial (NCT07519655) has an active research site in Denver, CO that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Non-Small-Cell Lung Treatment Options in Denver, CO

If you're searching for non-small-cell lung treatment options in Denver, CO, this clinical trial (NCT07519655) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Denver research site is actively enrolling participants for this clinical trial. You'll receive care from experienced non-small-cell lung specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all non-small-cell lung clinical trials near you to find additional studies recruiting in your area.

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