Charlottesville, VANCT06023186Now EnrollingIRB Ready

Obstructive Hypertrophic Cardiomyopathy Clinical Trial in Charlottesville, VA

Access cutting-edge obstructive hypertrophic cardiomyopathy treatment through this clinical trial at a research site in Charlottesville. Study-provided care at no cost to qualified participants.

Sponsored by Michael Ayers

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Expert Care in Charlottesville

Access obstructive hypertrophic cardiomyopathy specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related obstructive hypertrophic cardiomyopathy treatment provided free

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Check if you qualify for this obstructive hypertrophic cardiomyopathy clinical trial in Charlottesville, VA

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Why Participate?

  • No-Cost Study Care

  • Local to Charlottesville

    Convenient for VA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Charlottesville site if eligible
  4. 4Begin participation

About This Obstructive Hypertrophic Cardiomyopathy Study in Charlottesville

The goal of this observational study is to measure the effect of mavacamten treatment on blood flow in the heart muscle (myocardium) in patients with obstructive hypertrophic cardiomyopathy. The main question it aims to answer is: • Does mavacamten treatment improve blood flow in the heart muscle? Participants will take mavacamten at the direction of their treating physician. Participants will complete 2 myocardial Positron Emission Tomography and Computed Tomography (PET-CT) scans. The first scan will be completed before participants start taking mavacamten. The scan will be repeated after 12 months of mavacamten treatment.

Sponsor: Michael Ayers

Who Can Participate

Inclusion Criteria

Willingness and ability to provide written informed consent
Willingness and ability to comply with scheduled visits and study procedures
Male or female, aged 18-85 years
Diagnosed with obstructive hypertrophic cardiomyopathy according to presence of a left ventricular wall thickness of ≥15 mm that is otherwise unexplained by abnormal loading conditions (e.g., hypertension, valvular, congenital disease) or infiltrative cardiomyopathies. Unexplained left ventricular wall thickness of ≥13 mm is sufficient for diagnosis in relatives of individuals with hypertrophic cardiomyopathy or those who are genotype positive.
Has been prescribed mavacamten consistent with US Prescribing Information
Ability and intention to adhere to oral mavacamten therapy as prescribed by treating physician for the duration of study participation
For females of reproductive potential: negative pregnancy test at screening/baseline and 12 month visits.

Exclusion Criteria

Pregnancy or lactation
Known hypersensitivity to components of mavacamten or regadenoson
Prior treatment with mavacamten or aficamten 11\. Over weight limit for imaging gantry. 12. To minimize the risk of participants undergoing PET/CT with inadequate image quality, participants with left ventricular systolic dysfunction or lung disease will be excluded.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Charlottesville?

Yes, this clinical trial (NCT06023186) has an active research site in Charlottesville, VA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Obstructive Hypertrophic Cardiomyopathy Treatment Options in Charlottesville, VA

If you're searching for obstructive hypertrophic cardiomyopathy treatment options in Charlottesville, VA, this clinical trial (NCT06023186) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Charlottesville research site is actively enrolling participants for this clinical trial. You'll receive care from experienced obstructive hypertrophic cardiomyopathy specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all obstructive hypertrophic cardiomyopathy clinical trials near you to find additional studies recruiting in your area.

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