North Charleston, SCNCT04564989Now EnrollingIRB Ready

Oropharyngeal Squamous Cell Carcinoma Clinical Trial in North Charleston, SC

Access cutting-edge oropharyngeal squamous cell carcinoma treatment through this clinical trial at a research site in North Charleston. Study-provided care at no cost to qualified participants.

Sponsored by UNC Lineberger Comprehensive Cancer Center

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Expert Care in North Charleston

Access oropharyngeal squamous cell carcinoma specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related oropharyngeal squamous cell carcinoma treatment provided free

Apply for This North Charleston Location

Check if you qualify for this oropharyngeal squamous cell carcinoma clinical trial in North Charleston, SC

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to North Charleston

    Convenient for SC residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit North Charleston site if eligible
  4. 4Begin participation

About This Oropharyngeal Squamous Cell Carcinoma Study in North Charleston

The primary goal of this study is to examine whether recurrence of HPV-associated OPSCC can be predicted by two factors: 1) mutations in genes called TRAF3 and CYLD, and 2) measurements of circulating HPV DNA in blood plasma. The study will also investigate whether HPV integration is associated with TRAF3 and CYLD mutations, and whether recurrence prediction improves when looking at HPV integration along with TRAF3 and CYLD mutations.

Sponsor: UNC Lineberger Comprehensive Cancer Center

Who Can Participate

Inclusion Criteria

≥ 18 years of age
T0-T2 N2a-N3 M0 or T3-T4 N0-N3 M0 (AJCC 7th edition)
Biopsy proven squamous cell carcinoma of the oropharynx or unknown primary
No prior therapy
No evidence of distant metastatic disease
p16 positive = diffuse ≥ 70% tumor cell expression, with at least moderate (2/3+) staining intensity
Planned for receipt of definitive cancer treatment
ECOG Performance Status 0-1
Patients must be deemed able to comply with the treatment plan and follow-up schedule.
Patients must provide study specific informed consent prior to study entry

Exclusion Criteria

All subjects meeting any of the exclusion criteria at baseline will be excluded from study participation:
Prior history of radiation therapy to the head and neck
Prior history of head and neck cancer.
Inadequate pre-treatment tissue sample for tumor genomic analyses

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in North Charleston?

Yes, this clinical trial (NCT04564989) has an active research site in North Charleston, SC that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Oropharyngeal Squamous Cell Carcinoma Treatment Options in North Charleston, SC

If you're searching for oropharyngeal squamous cell carcinoma treatment options in North Charleston, SC, this clinical trial (NCT04564989) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our North Charleston research site is actively enrolling participants for this clinical trial. You'll receive care from experienced oropharyngeal squamous cell carcinoma specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all oropharyngeal squamous cell carcinoma clinical trials near you to find additional studies recruiting in your area.

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