New York, NYNCT04152551Now EnrollingIRB Ready

Osteogenesis Imperfecta Clinical Trial in New York, NY

Access cutting-edge osteogenesis imperfecta treatment through this clinical trial at a research site in New York. Study-provided care at no cost to qualified participants.

Sponsored by Hospital for Special Surgery, New York

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Expert Care in New York

Access osteogenesis imperfecta specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related osteogenesis imperfecta treatment provided free

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Check if you qualify for this osteogenesis imperfecta clinical trial in New York, NY

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to New York

    Convenient for NY residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit New York site if eligible
  4. 4Begin participation

About This Osteogenesis Imperfecta Study in New York

Osteogenesis Imperfecta-related hearing loss usually occurs in individuals with mild (type I) OI and is much earlier in onset than age-related hearing loss, with the majority of individuals experiencing some minor hearing loss in their 20s. Bisphosphonates have been successfully used to treat otosclerosis, a common cause of hearing loss similar to OI-related hearing loss. As many individuals with OI-related hearing loss also present with otosclerosis and because of their mechanistic similarities, the investigators propose studying the effects of bisphosphonate treatment on individuals diagnosed with both OI type I and hearing loss, thereby determining its effectiveness as a potential treatment for hearing loss. The investigators will enroll 50 individuals diagnosed with type I OI and age 18-100. 25 adults will be enrolled into the treatment arm and receive bisphosphonate treatment (must have at least mild hearing loss), while 25 adults will be enrolled into the control arm. The investigators will enroll 25 children (6-17 years of age) diagnosed with OI who are currently receiving bisphosphonate treatment as part of their care for orthopedic symptoms. The investigators will also observe 25 children (6-17 years of age) diagnosed with OI who are NOT currently receiving bisphosphonate treatment. The study duration is 63 months (approximately 5 years). Enrollment is anticipated to begin in November 2019.

Sponsor: Hospital for Special Surgery, New York

Who Can Participate

Inclusion Criteria

(Adult Treatment Arm):
Diagnosis of OI type I
Diagnosis of at least mild hearing loss (\>20dB pure tone average) by audiogram testing
Vitamin D level \> 30 Inclusion Criteria (Adult Control Arm):
Diagnosis of OI type I Inclusion Criteria (Child Observational Bisphosphonate Arm)
Diagnosis of OI
Age 6-17 years
Currently receiving bisphosphonate treatment as standard of care Inclusion Criteria (Child Observational No Treatment Arm)
Diagnosis of OI
Age 6-17 years
NOT receiving bisphosphonate treatment and will not receive bisphosphonate treatment for the duration of the study

Exclusion Criteria

(ALL ARMS):
Family history of hearing-loss (not related to OI or occupational hearing loss)

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in New York?

Yes, this clinical trial (NCT04152551) has an active research site in New York, NY that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Osteogenesis Imperfecta Treatment Options in New York, NY

If you're searching for osteogenesis imperfecta treatment options in New York, NY, this clinical trial (NCT04152551) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our New York research site is actively enrolling participants for this clinical trial. You'll receive care from experienced osteogenesis imperfecta specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all osteogenesis imperfecta clinical trials near you to find additional studies recruiting in your area.

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