Skokie, ILNCT07405554Now EnrollingIRB Ready

Overactive Bladder (OAB) Clinical Trial in Skokie, IL

Access cutting-edge overactive bladder (oab) treatment through this clinical trial at a research site in Skokie. Study-provided care at no cost to qualified participants.

Sponsored by Endeavor Health

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Expert Care in Skokie

Access overactive bladder (oab) specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related overactive bladder (oab) treatment provided free

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Check if you qualify for this overactive bladder (oab) clinical trial in Skokie, IL

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Why Participate?

  • No-Cost Study Care

  • Local to Skokie

    Convenient for IL residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Skokie site if eligible
  4. 4Begin participation

About This Overactive Bladder (OAB) Study in Skokie

This randomized, double-blind, placebo-controlled trial evaluates whether oral zinc plus phytase supplementation modifies clinical response to intradetrusor botulinum toxin injection in patients with overactive bladder. Participants will receive either zinc plus phytase supplementation or matching placebo for five days prior to intradetrusor botulinum toxin injection. Participants will be followed for six months after treatment to assess need for repeat botulinum toxin injection, urinary symptoms, and patient-reported outcomes related to overactive bladder.

Sponsor: Endeavor Health

Who Can Participate

Inclusion Criteria

Non-pregnant adult female at least 21 years old, with no plans to become pregnant during the course of the trial) and if of child-bearing potential, with a negative pregnancy test, and if sexually active, must be using medically acceptable contraception.
≥ 6 urgency urinary incontinence episodes on a 3-day baseline bladder diary, with these urge incontinence episodes representing greater than 50% of the total incontinent episodes recorded.
Willing and able to complete all study related items and interviews.
Refractory urgency urinary incontinence: defined as persistent symptoms despite at least one or more conservative treatments (e.g. supervised behavioral therapy, supervised physical therapy)
Persistent symptoms despite the use of a minimum of two anticholinergics, or unable to tolerate medication due to side effects, or has a contraindication to taking anticholinergic/Beta 3 agonist medication.
Currently not on an anticholinergic or antimuscarinic/Beta 3 agonist medication (e.g. oxybutynin, tolterodine, darifenacin, trospium chloride, solifenacin-succinate, fesoterodine and/or mirabegron) or be willing to stop medication for 3 weeks prior to completing baseline bladder diary and expected to remain off medications through duration of study.
Demonstrates ability (or have caregiver demonstrate ability) to perform clean intermittent self-catheterization.
Grossly neurologically normal on exam and no gross systemic neurologic conditions believed to affect urinary function.

Exclusion Criteria

Neurologic diseases such as multiple sclerosis, Parkinson Disease, CVA within 6 months prior to enrollment, myasthenia gravis, Charcot-Marie-Tooth disease, clinically significant peripheral neuropathy, and complete spinal cord injury.
Untreated urinary tract infection (UTI).
Any prior use of either study therapy for treatment of urinary urge incontinence (Botox A® or Interstim®).
PVR \>150 ml on 2 occasions within 6 months prior to enrollment (If the PVR value was obtained by ultrasound and was ≥150 ml, the PVR will be confirmed by catheterization which will be the gold standard).
Current or prior bladder malignancy.
Surgically altered detrusor muscle, such as augmentation cystoplasty.
Subjects taking aminoglycosides.
Currently pregnant or lactating.
Allergy to lidocaine or bupivacaine.
Prior pelvic radiation.
Uninvestigated hematuria.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Skokie?

Yes, this clinical trial (NCT07405554) has an active research site in Skokie, IL that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Overactive Bladder (OAB) Treatment Options in Skokie, IL

If you're searching for overactive bladder (oab) treatment options in Skokie, IL, this clinical trial (NCT07405554) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Skokie research site is actively enrolling participants for this clinical trial. You'll receive care from experienced overactive bladder (oab) specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all overactive bladder (oab) clinical trials near you to find additional studies recruiting in your area.

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