Escondido, CANCT07441252Now EnrollingIRB Ready

Overweight or Obesity and Elevated Liver Fat Clinical Trial in Escondido, CA

Access cutting-edge overweight or obesity and elevated liver fat treatment through this clinical trial at a research site in Escondido. Study-provided care at no cost to qualified participants.

Sponsored by Amgen

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Expert Care in Escondido

Access overweight or obesity and elevated liver fat specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related overweight or obesity and elevated liver fat treatment provided free

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Check if you qualify for this overweight or obesity and elevated liver fat clinical trial in Escondido, CA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Escondido

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Escondido site if eligible
  4. 4Begin participation

About This Overweight or Obesity and Elevated Liver Fat Study in Escondido

The main objective of this trial will be to determine whether maridebart cafraglutide is superior to placebo on reduction in liver fat content and body weight in participants living with obesity or overweight and elevated liver fat content, when administered in conjunction with reduced-calorie diet and increased physical activity.

Sponsor: Amgen

Who Can Participate

Inclusion Criteria

Age ≥ 18 years.
Body Mass index (BMI) ≥ 27 kg/m\^2 to ≤ 40 kg/m\^2 at screening.
For participants with type 2 diabetes mellitus (T2DM) at screening:
HbA1c ≤ 9.5% (80 mmol/mol) at screening.
Treated with diet and exercise alone and/or a stable treatment with metformin, sodium-glucose cotransporter-2 (SGLT-2) inhibitors, or combination.
Liver Controlled Attenuation Parameter (CAPTM) ≥ 300 dB/meter via FibroScan® assessment.
Liver fat content ≥ 10% by MRI as determined by the central imaging vendor at screening.
MRI assessment should only be performed after all other eligibility has been confirmed whenever possible.
History of at least 1 self-reported unsuccessful attempt at weight loss by diet and exercise.

Exclusion Criteria

Recent or planned surgical/device-based obesity treatment (\<1 year).
History of malignancy within the past 5 years (exceptions apply).
Type 1 diabetes or non-type 2 diabetes mellitus (T2DM); unstable/severe hypoglycemia.
Advanced diabetic retinopathy or macular edema.
History of pancreatitis (acute \<180 days or chronic).
History of medullary thyroid carcinoma (MTC) or MEN-2
Major cardiovascular event within 60 days (e.g., myocardial infarction \[MI\], stroke, coronary artery bypass graft \[CABG\]).
New York Heart Association (NYHA) Class IV heart failure.
Unstable psychiatric disorders within 2 years.
Significant liver disease other than metabolic dysfunction-associated steatotic liver disease (MASLD) (e.g., hepatitis, cirrhosis, hepatic decompensation).
Estimated glomerular filtration rate (eGFR) \< 30 mL/min/1.73 m\^2 or on dialysis.
Patient Health Questionnaire-9 (PHQ-9) ≥ 15, or suicidal ideation/behavior (Columbia-Suicide Severity Rating Scale \[C-SSRS\]).
Inability to undergo MRI scan (e.g., due to metal implant, claustrophobia, or body size limitations).

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Escondido?

Yes, this clinical trial (NCT07441252) has an active research site in Escondido, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Overweight or Obesity and Elevated Liver Fat Treatment Options in Escondido, CA

If you're searching for overweight or obesity and elevated liver fat treatment options in Escondido, CA, this clinical trial (NCT07441252) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Escondido research site is actively enrolling participants for this clinical trial. You'll receive care from experienced overweight or obesity and elevated liver fat specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all overweight or obesity and elevated liver fat clinical trials near you to find additional studies recruiting in your area.

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