Minneapolis, MNNCT07226284Now EnrollingIRB Ready

PARKINSON DISEASE (Disorder) Clinical Trial in Minneapolis, MN

Access cutting-edge parkinson disease (disorder) treatment through this clinical trial at a research site in Minneapolis. Study-provided care at no cost to qualified participants.

Sponsored by University of Minnesota

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Expert Care in Minneapolis

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IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related parkinson disease (disorder) treatment provided free

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Check if you qualify for this parkinson disease (disorder) clinical trial in Minneapolis, MN

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Why Participate?

  • No-Cost Study Care

  • Local to Minneapolis

    Convenient for MN residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Minneapolis site if eligible
  4. 4Begin participation

About This PARKINSON DISEASE (Disorder) Study in Minneapolis

This study is designed to better understand the mechanisms contributing to impaired activation of leg muscles in people with Parkinson's disease (PD) and to test if stimulation of a nerve at the neck can improve muscle activation, walking and balance.

Sponsor: University of Minnesota

Who Can Participate

Inclusion Criteria

Diagnosis of idiopathic Parkinson's disease,
On stable medication for the preceding month and anticipated over the next 3 months,
Able to ambulate without the use of an assistive device for more than 50 meters. Control Cohort:
Age (± 3 years) and sex distribution matched to the PD cohort,
Able to ambulate without the use of an assistive device for more than 50 meters.

Exclusion Criteria

Failure to demonstrate capacity to consent (based on UBACC and/or MacArthur-CR),
History of significant neurological disorder (besides PD in the PD group),
History of stroke, traumatic brain injury, intracranial aneurysm, intracranial hemorrhage, brain tumor or atypical parkinsonian disorder,
Severe orthopedic or other related musculoskeletal pathology that has significant adverse effects on gait,
Women who are pregnant or may be pregnant,
Insufficient comprehension of the English language,
History of substance abuse in past 2 years; Additional exclusion criteria for VNS experiment
Pain at the nVNS treatment site (e.g., dysesthesia, neuralgia, cervicalgia);
Lesion (including lymphadenopathy), previous surgery (including carotid endarterectomy or vascular neck surgery) or abnormal anatomy at the stimulation site (open wound, rash, infection, swelling, cut, sore, drug patch, surgical scar\[s\]);
Known or suspected severe atherosclerotic cardiovascular disease, severe carotid artery disease (e.g., bruits or history of TIA or stroke), congestive heart failure, known severe coronary artery disease or prior myocardial infarction;
Abnormal baseline electrocardiogram (ECG) within the last year (e.g., second or third-degree heart block, prolonged QT interval, atrial fibrillation, atrial flutter, history of ventricular tachycardia or ventricular fibrillation);
Recent history of uncontrolled high blood pressure, bradycardia, tachycardia, or know recent history orthostatic hypotension;
Previous unilateral or bilateral vagotomy;
Implanted metal cervical spine hardware, other metallic implants or implantable medical devices such as deep brain stimulator, hearing aid implant, pacemaker, implanted cardioverter defibrillator, cranial aneurysm and/or cranial aneurysm clips, history of facial/orbital/metallic fragments, implanted electronic device, neurostimulator, valve replacements/stents, metallic implants/prostheses) near the stimulation site such as a bone plate or bone screw;
History of syncope or seizures (within the last 2 years);

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Minneapolis?

Yes, this clinical trial (NCT07226284) has an active research site in Minneapolis, MN that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

PARKINSON DISEASE (Disorder) Treatment Options in Minneapolis, MN

If you're searching for parkinson disease (disorder) treatment options in Minneapolis, MN, this clinical trial (NCT07226284) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Minneapolis research site is actively enrolling participants for this clinical trial. You'll receive care from experienced parkinson disease (disorder) specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all parkinson disease (disorder) clinical trials near you to find additional studies recruiting in your area.

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