Avondale, AZNCT07318610Now EnrollingIRB Ready

Peripheral Artery Disease (PAD) Clinical Trial in Avondale, AZ

Access cutting-edge peripheral artery disease (pad) treatment through this clinical trial at a research site in Avondale. Study-provided care at no cost to qualified participants.

Sponsored by Regeneron Pharmaceuticals

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Expert Care in Avondale

Access peripheral artery disease (pad) specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related peripheral artery disease (pad) treatment provided free

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Check if you qualify for this peripheral artery disease (pad) clinical trial in Avondale, AZ

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Why Participate?

  • No-Cost Study Care

  • Local to Avondale

    Convenient for AZ residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Avondale site if eligible
  4. 4Begin participation

About This Peripheral Artery Disease (PAD) Study in Avondale

This study is researching 2 different experimental drugs called REGN7508 and REGN9933. The study is focused on people who have Peripheral Artery Disease (PAD), which means that the blood vessels in their arms and legs have become too narrow. People with PAD have a higher risk of getting blood clots after procedures like Lower Extremity Revascularization (LER), a procedure to improve blood flow in the legs and feet. The aim of this study is to see how well REGN7508 and REGN9933 prevent life-threatening blood clots in participants with PAD who have recently had LER. The effects of REGN7508 and REGN9933, individually, will also be compared to rivaroxaban and a placebo. The study is looking at several other research questions, including: * What side effects might happen from taking the study drugs and how do they compare to the side effects of rivaroxaban * How much study drug is in the blood at different times * Whether the body makes antibodies against the study drugs (which could make the drugs less effective or could lead to side effects) * If the study drugs affect the ability of the blood to clot normally

Sponsor: Regeneron Pharmaceuticals

Who Can Participate

Inclusion Criteria

Successful LER distal to the external iliac artery for ischemia due to atherosclerotic disease within 10 days prior to randomization as described in the protocol
At least 1 of the following enrichment factors for major thrombotic vascular events:
Bypass with prosthetic graft
Endovascular treatment with stenting
Target lesion length \>15 cm
History of LER or amputation for PAD prior to qualifying LER
Type 2 diabetes mellitus requiring pharmacologic treatment
Comorbid symptomatic coronary artery disease as described in the protocol
Chronic kidney disease as described in the protocol
Age ≥75 years Key

Exclusion Criteria

Has any active clinical condition requiring chronic therapeutic anticoagulation after the index revascularization including known triple positive antiphospholipid syndrome
Has known bleeding diathesis, platelet count \<50,000/mm\^3 or history of non-traumatic intracerebral hemorrhage, known cerebral amyloid angiopathy, or known unrepaired cerebrovascular malformations
Has recent coronary revascularization as described in the protocol
For Cohort 2 only: Has estimated Glomerular Filtration Rate (eGFR) \<15 mL/min/1.73m\^2 within 14 days prior to randomization or on dialysis or expected to be started on dialysis within the next 12 weeks starting from randomization
Has any other condition or therapy which would make the participant unsuitable for this study or not allow participation for the full planned study period
Has allergy, hypersensitivity, or other contraindication to REGN7508, REGN9933, or rivaroxaban (Cohort 2 only) or their excipients Note: Other Protocol Defined Inclusion/ Exclusion Criteria Apply

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Avondale?

Yes, this clinical trial (NCT07318610) has an active research site in Avondale, AZ that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Peripheral Artery Disease (PAD) Treatment Options in Avondale, AZ

If you're searching for peripheral artery disease (pad) treatment options in Avondale, AZ, this clinical trial (NCT07318610) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Avondale research site is actively enrolling participants for this clinical trial. You'll receive care from experienced peripheral artery disease (pad) specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all peripheral artery disease (pad) clinical trials near you to find additional studies recruiting in your area.

More Peripheral Artery Disease Trials in Avondale, AZ

See all peripheral artery disease clinical trials recruiting in Avondale — not just this study.

Browse Peripheral Artery Disease Trials in Avondale

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