Hartford, CTNCT06479161Now EnrollingIRB Ready

Postoperative Pain Clinical Trial in Hartford, CT

Access cutting-edge postoperative pain treatment through this phase 2 clinical trial at a research site in Hartford. Study-provided care at no cost to qualified participants.

Sponsored by Matthew Grosso, MD

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Expert Care in Hartford

Access postoperative pain specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related postoperative pain treatment provided free

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Check if you qualify for this postoperative pain clinical trial in Hartford, CT

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Hartford

    Convenient for CT residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Hartford site if eligible
  4. 4Begin participation

About This Postoperative Pain Study in Hartford

The primary purpose of this study is to evaluate postoperative pain. Secondary outcomes evaluated in this study will include range of motion (ROM), opioid consumption, and ambulation. Each outcome measure will be evaluated, oral tranexamic acid (TXA) in the experiment arm and placebo in the control arm, after total knee arthroplasty (TKA) at postoperative days 0-3, and weeks 1, 2, 6, and 12.

Sponsor: Matthew Grosso, MD

Who Can Participate

Inclusion Criteria

\- All patients undergoing either manual or robotic primary total knee arthroplasty (TKA)
Performed by participating Connecticut Joint Replacement Institute (CJRI) surgeons (Dr. Matthew Grosso, Dr. Robert McAllister, Dr. Chad Daniel, Dr. Eric Silverstein, Dr. Alex Dukas, Dr. Michael Joyce, Dr. Brett Wasserlauf).
Male and female patient age 18-89
Primary diagnosis of knee osteoarthritis

Exclusion Criteria

Revision TKA
No exclusion based on gender
Patients \<18 and \>89 years old
TXA allergy - there are NO absolute contraindications for TXA use.
History of stent placed within one year of surgery - patient will receive topical TXA as an alternative.
Chronic opioid use (opioid use within the 4 weeks prior to surgery)
Allergies to nonsteroidal Anti-inflammatory drugs (NSAIDs) and acetaminophen
Patients with clinically significant drug interactions
Pre-existing neuropathy
Current or previous venous thrombosis (DVT or venous stasis disease)
Immuno-compromised secondary to medical condition
Immune-suppressive medications, chemotherapy
Pregnancy, breast feeding
History of pain catastrophizing. Major depressive disorder
History of suspected or known addiction to or abuse of illicit drug(s), prescription medicine(s), or alcohol within the past 2 years.
Currently on a neuroleptic agent \[e.g., gabapentin, pregabalin (Lyrica), duloxetine (Cymbalta) etc.\].
Non-English speaking and reading patient populations
Any clinically significant event or condition uncovered during the surgery (e.g., excessive bleeding, acute sepsis) that, in the opinion of the investigator, renders the subject medically unstable or complicates the subject's post-operative course.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Hartford?

Yes, this clinical trial (NCT06479161) has an active research site in Hartford, CT that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Postoperative Pain Treatment Options in Hartford, CT

If you're searching for postoperative pain treatment options in Hartford, CT, this clinical trial (NCT06479161) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Hartford research site is actively enrolling participants for this phase 2 clinical trial. You'll receive care from experienced postoperative pain specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all postoperative pain clinical trials near you to find additional studies recruiting in your area.

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