Worcester, MANCT07210255Now EnrollingIRB Ready

Postpartum Depression (PPD) Clinical Trial in Worcester, MA

Access cutting-edge postpartum depression (ppd) treatment through this clinical trial at a research site in Worcester. Study-provided care at no cost to qualified participants.

Sponsored by Magnus Medical

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Expert Care in Worcester

Access postpartum depression (ppd) specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related postpartum depression (ppd) treatment provided free

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Check if you qualify for this postpartum depression (ppd) clinical trial in Worcester, MA

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Why Participate?

  • No-Cost Study Care

  • Local to Worcester

    Convenient for MA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Worcester site if eligible
  4. 4Begin participation

About This Postpartum Depression (PPD) Study in Worcester

This study is a large, multi-site clinical trial testing whether Stanford Accelerated Intelligent Neuromodulation Therapy (SAINT), a fast-acting form of repetitive transcranial magnetic stimulation (rTMS), can more effectively reduce symptoms of postpartum depression (PPD) compared to a sham treatment. It will enroll 192 women within 12 months postpartum who are experiencing depression that has not improved with standard care, and will track their progress for up to 12 months. The trial's main goal is to see if SAINT leads to reduction in depression severity in women with postpartum depression.

Sponsor: Magnus Medical

Who Can Participate

Inclusion Criteria

Reproductive Women ages 18-45 at the time of consent.
Diagnosis of non-psychotic Major Depressive Episode (MDE) with peripartum onset as assessed through the Quick Structured Clinical Interview for DSM-5.
0-12 months postpartum. Participants must be 0-12 months postpartum at screening and remain within 12 months postpartum at the 5-day post-treatment visit.
If currently taking an antidepressant medication and/or receiving psychotherapy must be on a stable regimen for 30 days at the time of enrollment.
Severe depression as measured by MADRS ≥20 at screening.
A good candidate for repetitive transcranial magnetic stimulation (rTMS) as determined by a physician.
Participants must be capable of giving informed consent. Participants must be proficient in English in order to comprehend study requirements.
Agree to use effective contraception in the postpartum period for the study duration.
Willing and able to comply with all study procedures, complete required assessments and visits, and be available for the duration of the study.

Exclusion Criteria

Participant has attempted suicide in the last 6 months and/or expressed suicidal ideation with intent as determined by physician assessment at the time of enrollment.
Score of 6 on MADRS item 10 (high rating of suicidal ideation) at screening.
Participant has active psychosis per investigator assessment.
Participant with a primary lifetime diagnosis of bipolar disorder, schizophrenia, schizoaffective disorder and/or obsessive-compulsive disorder.
Participant has an active eating disorder or substance use disorder in the past 6 months and/or has a positive urine toxicity screen that the Principal Investigator (PI) deems exclusionary.
Participant is using any exclusionary medications: high dose of benzodiazepines (\>2mg lorazepam daily equivalent and/or \>3 times per week) or medications that would interfere with treatment with TMS as per PI or designee discretion.
Participant has a history of untreated or insufficiently treated sleep apnea.
Participant has a history of significant neurologic disease, including developmental disability, dementia, Parkinson's or Huntington's disease, brain tumor, unexpected seizure/epilepsy disorder, subdural hematoma, multiple sclerosis, or history of significant head trauma.
Any untreated major somatic illness such as hypertension/cardiovascular disease/diabetes/endocrine disorders etc.
Contraindications to receiving rTMS (e.g., metal in head, history of seizure, known brain lesion).
Contraindications to MRI (e.g., ferromagnetic metal in their body).
Currently pregnant.
History of receiving rTMS for any reason, as this may compromise blinding.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Worcester?

Yes, this clinical trial (NCT07210255) has an active research site in Worcester, MA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Postpartum Depression (PPD) Treatment Options in Worcester, MA

If you're searching for postpartum depression (ppd) treatment options in Worcester, MA, this clinical trial (NCT07210255) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Worcester research site is actively enrolling participants for this clinical trial. You'll receive care from experienced postpartum depression (ppd) specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all postpartum depression (ppd) clinical trials near you to find additional studies recruiting in your area.

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