NCT07766161 · University of Michigan
Informing Implementation of a Circadian-Focused Intervention for Postpartum Depression
What this study is about
The proposed study is an where both patients and doctors know the treatment given trial of Re-Timer® wearable morning bright light therapy for postpartum depression. The study is focused on evaluating the feasibility, acceptability, and implementation context of morning Bright Light Treatment (mBLT) for postpartum depression.
View original scientific description
The proposed study is an open-label trial of Re-Timer® wearable morning bright light therapy for postpartum depression. The study is focused on evaluating the feasibility, acceptability, and implementation context of morning Bright Light Treatment (mBLT) for postpartum depression.
Interventions
DEVICE
Light therapy
Participants will use the Re-Timer daily for 5 weeks (approximately 35 days). All participants will be provided with a "light therapy window" during which they will wear the device for 60 mins.
Primary outcome measures
Retention rate
Time frame: At approximately 5 weeks after treatment is started (post-treatment)
Number of participants who enrolled/number of participants who completed trial ( ≥70% acceptable)
Adherence rate (as assessed through self-report)
Time frame: At approximately 5 weeks after treatment is started (post-treatment)
Percent of participants who completed ≥70% light therapy intervention sessions
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- ≤ 6 months postpartum
- EPDS score \>10
Exclusion criteria
- Current or past-year substance use disorder
- Lifetime history of bipolar disorder or psychotic disorder
- Active suicidal intent
- Retinal pathology or history of eye surgery
- Current use of photosensitizing medications
- Untreated sleep-disordered breathing, untreated restless legs syndrome, or narcolepsy
- Psychotherapy or psychotropic medications started/dose changed in past month (psychotherapy started and/or current medication at stable dose ≥ 4 weeks are permitted)
- Medical conditions contraindicated for mBLT (e.g., epilepsy/seizures)
Where
- Ann Arbor, Michigan
Collaborators
American Academy of Sleep Medicine
Related conditions & keywords
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Aug 14, 2026 · Source of record for eligibility and locations