Philadelphia, PANCT06408181Now EnrollingIRB Ready

Pre-Eclampsia Clinical Trial in Philadelphia, PA

Access cutting-edge pre-eclampsia treatment through this clinical trial at a research site in Philadelphia. Study-provided care at no cost to qualified participants.

Sponsored by University of Pennsylvania

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Expert Care in Philadelphia

Access pre-eclampsia specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related pre-eclampsia treatment provided free

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Check if you qualify for this pre-eclampsia clinical trial in Philadelphia, PA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Philadelphia

    Convenient for PA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Philadelphia site if eligible
  4. 4Begin participation

About This Pre-Eclampsia Study in Philadelphia

The goal of this clinical trial is to investigate the effects of early initiation of double low-dose aspirin in pregnant women. The main questions it aims to answer are: Does this dose and timing of aspirin reduce the risk of pre-eclampsia compared to standard recommendations? Does this dose and timing of aspirin reduce the risk of pregnancy loss compared to standard recommendations? Participants will begin taking at no later than 6 weeks 6 days gestational age, either 162mg of aspirin through delivery or placebo until 12 weeks and then 81mg of aspirin through delivery.

Sponsor: University of Pennsylvania

Who Can Participate

Inclusion Criteria

Provision of signed and dated informed consent form.
Stated willingness to comply with all study procedures and availability for the duration of the study.
Ability to take oral medication and be willing to adhere to the prescribed aspirin regimen.
Patients with a gestation less than or equal to 6 weeks, 6 days (as determined by patient record of LMP or ART date).
Patients between 18-45-year old who have one or more risk factors for preeclampsia and/or pregnancy loss, including:
preeclampsia in a previous pregnancy,
gestational diabetes in a previous pregnancy,
any documentation of fetal growth restriction or low birth weight in a prior pregnancy,
preterm birth in a previous pregnancy,
known multifetal gestation at enrollment,
chronic hypertension,
pregestational diabetes,
kidney disease,
systemic lupus erythematosus,
nulliparity,
pre-pregnancy body mass index \>30,
family history of preeclampsia (i.e., mother or sister),
Black persons (due to social, not biological reasons),
Maternal age 35 years or older,
lower income (will be determined by qualification of public health insurance),
conceived with fertility treatment (including in vitro fertilization, ovulation induction, or intrauterine insemination),
history of one or more prior pregnancy losses \<20 weeks gestation,
history of stillbirth in a prior pregnancy,
An interval of greater than 10 years since the last pregnancy.

Exclusion Criteria

Known allergies to aspirin or non-steroidal anti-inflammatory agents (NSAID);
Clinical indication for anticoagulant therapy, including prior or current thrombosis, antiphospholipid syndrome, or known major thrombophilia;
Clinical indication for chronic use of NSAIDS during pregnancy;
Medical contraindication to aspirin therapy, including untreated uncontrolled asthma, untreated symptomatic nasal polyps, bleeding disorders, or history of gastrointestinal ulcer.
Patients with pelvic pain or bleeding who require urgent care (i.e., active vaginal bleeding greater than or equal to expected menses, open cervical os suggesting active miscarriage or severe pain requiring evaluation for ectopic pregnancy)

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Philadelphia?

Yes, this clinical trial (NCT06408181) has an active research site in Philadelphia, PA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Pre-Eclampsia Treatment Options in Philadelphia, PA

If you're searching for pre-eclampsia treatment options in Philadelphia, PA, this clinical trial (NCT06408181) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Philadelphia research site is actively enrolling participants for this clinical trial. You'll receive care from experienced pre-eclampsia specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all pre-eclampsia clinical trials near you to find additional studies recruiting in your area.

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