NCT06735651 · Georgia State University
Wild Blueberries for Gut, Brain, and Cardiometabolic Health in Prediabetes
What this study is about
The goal of this clinical trial is to determine the effectiveness of using a freeze-dried wild blueberry powder on cardiometabolic health, cognitive function, and gut microbiota composition in adult women with prediabetes.
View original scientific description
The goal of this clinical trial is to determine the effectiveness of using a freeze-dried wild blueberry powder on cardiometabolic health, cognitive function, and gut microbiota composition in adult women with prediabetes.
Interventions
DIETARY_SUPPLEMENT
Wild Blueberry
Daily consumption of 22 g of freeze-dried wild blueberry freeze-dried powder for 6 weeks
DIETARY_SUPPLEMENT
Placebo
Daily consumption of 22 g of freeze-dried macronutrient-matched placebo powder for 6 weeks
Primary outcome measures
Blood Glucose
Time frame: Baseline and 6 weeks
Measurement of fasting blood glucose
Ambulatory Blood Pressure
Time frame: Baseline and 6 weeks
Assessment of whole-day ambulatory blood pressure during daytime and nighttime periods.
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- Women aged 20-65 years old
- Prediabetes (fasting blood glucose 100-125 mg/dL and/or HbA1c percentage between 5.7-6.4)
- Body Mass Index between 25-30 kg/m\^2
Exclusion criteria
- Allergies to berries
- Use of insulin, antidiabetic, antibiotics, and anti-inflammatory drugs
- Active cancer, gastrointestinal, renal, thyroid, stage 1 \& 2 hypertension and other cardiovascular diseases, neurological diseases, or severe head injury
- Consumes greater than 2 alcoholic beverages per day
- Consumes antioxidant, probiotic, and prebiotic supplements
- Pregnant or Lactating
- Actively participating in a weight loss program
- Currently taking berry supplements or recently participated in another study taking berry supplements
Where
- Atlanta, Georgia
Collaborators
Wild Blueberry Association of North America
Related conditions & keywords
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Mar 25, 2026 · Source of record for eligibility and locations