Cincinnati, OHNCT07214311Now EnrollingIRB Ready

Prosthetic-joint Infection Clinical Trial in Cincinnati, OH

Access cutting-edge prosthetic-joint infection treatment through this clinical trial at a research site in Cincinnati. Study-provided care at no cost to qualified participants.

Sponsored by Peptilogics

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Expert Care in Cincinnati

Access prosthetic-joint infection specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related prosthetic-joint infection treatment provided free

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Check if you qualify for this prosthetic-joint infection clinical trial in Cincinnati, OH

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Cincinnati

    Convenient for OH residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Cincinnati site if eligible
  4. 4Begin participation

About This Prosthetic-joint Infection Study in Cincinnati

The goal of this clinical trial is to evaluate whether the investigational drug PLG0206 can help reduce recurrence of infection in adults who have undergone total knee replacement and are receiving a DAIR (Debridement, Antibiotics, and Implant Retention) surgical procedure to treat a Prosthetic Joint Infection (PJI). The study will also assess the safety of PLG0206 when used as an irrigation solution during the DAIR procedure. Participants will receive either PLG0206 or a placebo (an inactive substance that looks like the investigational drug), in addition to standard of care treatments. All participants will be monitored for approximately one year following their DAIR procedure.

Sponsor: Peptilogics

Who Can Participate

Inclusion Criteria

Male or female participants age between 18 and \<80 years
Able to provide informed consent, geographically stable, and able to comply with the required follow-up visits
Suspected or confirmed PJI of the knee
Well-fixed and positioned prosthesis and good condition of surrounding soft tissue (no sinus tract)
A single DAIR procedure is indicated as treatment of PJI
Agree to use contraceptives if of childbearing potential

Exclusion Criteria

Loose prosthesis or surgical treatment planned for removal of well-fixed, nonmodular implants
Anticipated to require antibiotic therapy for \>6 months after DAIR procedure
Infection spread beyond the affected knee joint (e.g., osteomyelitis)
History of a prior PJI of the affected knee
Two or more prior revisions in the affected joint
Epithelialized sinus tract with evidence of communication to the joint or visualization of prosthesis
Diabetes mellitus and with an A1c ≥9%
History of malignant disease and having received immunosuppressive therapy, radiation therapy, or chemotherapy within the past year
Known immunodeficiency (e.g., splenectomy; sickle cell anemia; human immunodeficiency virus \[HIV\] with recent CD4 count \<200 cells/mm3; or primary humoral, bone marrow, or other transplantation)

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Cincinnati?

Yes, this clinical trial (NCT07214311) has an active research site in Cincinnati, OH that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Prosthetic-joint Infection Treatment Options in Cincinnati, OH

If you're searching for prosthetic-joint infection treatment options in Cincinnati, OH, this clinical trial (NCT07214311) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Cincinnati research site is actively enrolling participants for this clinical trial. You'll receive care from experienced prosthetic-joint infection specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all prosthetic-joint infection clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Cincinnati, OH