Tampa, FLNCT07143448Now EnrollingIRB Ready

Pulmonary Arterial Hypertension Clinical Trial in Tampa, FL

Access cutting-edge pulmonary arterial hypertension treatment through this phase 1/2 clinical trial at a research site in Tampa. Study-provided care at no cost to qualified participants.

Sponsored by 35Pharma Inc

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Expert Care in Tampa

Access pulmonary arterial hypertension specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related pulmonary arterial hypertension treatment provided free

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Check if you qualify for this pulmonary arterial hypertension clinical trial in Tampa, FL

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Tampa

    Convenient for FL residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Tampa site if eligible
  4. 4Begin participation

About This Pulmonary Arterial Hypertension Study in Tampa

Phase 1b/2 Study of HS235 Assessing the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of the Activin Signaling Inhibitor HS235 Added to Background Treatment in Adults with Pulmonary Arterial Hypertension (PAH)

Sponsor: 35Pharma Inc

Who Can Participate

Inclusion Criteria

Participants are eligible to be included in the study only if they meet all of the following criteria:
Male and female participants, 18 years of age and older.
Body Mass Index (BMI) 18.5 and 40 kg/m2 and body weight at or below 120 kg.
Baseline RHC performed during the Screening Period documenting:
A minimum PVR of ≥ 5 Wood units (WU) or ≥ 400 dyn·sec·cm-5 and,
A pulmonary artery wedge pressure (PAWP) of ≤ 15 mm Hg.
Diagnosis of WHO pulmonary arterial hypertension (PAH) Group 1.
Symptomatic PAH classified as WHO Functional class II to IV.
On stable doses of at least 2 approved background PAH therapies and diuretics.
6-Minute Walk Distance (6MWD) ≥ 150 m and ≤ 500 m repeated twice during screening.
Ability to adhere to study visit schedule and understand and comply with all protocol requirements.

Exclusion Criteria

PH WHO Groups 2, 3, 4 or 5.
Hospitalization for any worsening medical condition or major surgery within 4 weeks prior to screening.
Any symptomatic coronary disease events.
History of heart transplant or on heart transplant list.
Uncontrolled systemic hypertension.
History of restrictive, constrictive or congestive cardiomyopathy.
History of significant mitral regurgitation or aortic regurgitation valvular disease.
Untreated or poorly controlled moderate or severe obstructive sleep apnea.
A diagnosis of worse than moderate COPD or worse than mild ILD.
Cerebrovascular event within 90 days prior to screening
A pneumonectomy or lobectomy
Having received an activin signaling inhibitor such as sotatercept at any time prior to screening
A Hgb \> sex-specific ULN
Platelets count \< 100,000/mm3
Severe (stage ≥4) renal failure with eGFR \< 30 mL/min/m2
Abnormally elevated liver function enzymes (ALT or AST \> 3X ULN, or total bilirubin \> 1.5X ULN).

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Tampa?

Yes, this clinical trial (NCT07143448) has an active research site in Tampa, FL that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Pulmonary Arterial Hypertension Treatment Options in Tampa, FL

If you're searching for pulmonary arterial hypertension treatment options in Tampa, FL, this clinical trial (NCT07143448) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Tampa research site is actively enrolling participants for this phase 1/2 clinical trial. You'll receive care from experienced pulmonary arterial hypertension specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all pulmonary arterial hypertension clinical trials near you to find additional studies recruiting in your area.

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