Kansas City, MONCT07123779Now EnrollingIRB Ready

Pulmonary Hypertension Clinical Trial in Kansas City, MO

Access cutting-edge pulmonary hypertension treatment through this phase 1/2 clinical trial at a research site in Kansas City. Study-provided care at no cost to qualified participants.

Sponsored by 35Pharma Inc

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Expert Care in Kansas City

Access pulmonary hypertension specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related pulmonary hypertension treatment provided free

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Check if you qualify for this pulmonary hypertension clinical trial in Kansas City, MO

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Why Participate?

  • No-Cost Study Care

  • Local to Kansas City

    Convenient for MO residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Kansas City site if eligible
  4. 4Begin participation

About This Pulmonary Hypertension Study in Kansas City

Study of HS235 in Obese Participants with Pulmonary Hypertension and Heart Failure with Preserved Ejection Fraction

Sponsor: 35Pharma Inc

Who Can Participate

Inclusion Criteria

Participants are eligible to be included in the study only if they meet at least all the following criteria:
Male or female, ≥ 18 years of age.
\[Sub-population A only - using a remote PAP sensor\]- Ambulatory PAP monitoring (e.g., CardioMEMS™ HF System or Cordella™ HF System) implanted in the course of standard of care at least 90 days before Screening. Hemodynamic evidence of PH with:
mPAP ≥ 25 mm Hg, as measured in supine position by the averaged 7-day values (weekly average) 2 weeks and 1 week before Randomization AND,
dPAP ≥ 15 mm Hg, as measured in supine position by the averaged 7-day values (weekly average) 2 weeks and 1 week before Randomization.
\[Sub-population B only - without a remote PAP sensor\] Hemodynamic evidence of PH based on the presence of all the following RHC parameters obtained during the Screening period, prior to randomization:
PVR ≥ 240 dyn\*sec/cm5 or ≥ 3 WU, and
mPAP \> 20 mmHg, and
PAWP \> 15 mmHg but \< 30 mmHg, and
dPAP ≥ 15 mmHg.
Established diagnosis of HFpEF with left ventricular ejection fraction (LVEF) ≥ 45 % as measured by echocardiography during Screening and and no documented LVEF \< 45% during the 2 years preceding Screening..
New York Heart Association (NYHA) class II or III heart failure symptoms.
Stable diuretic regimen during the screening period.
Kansas City Cardiomyopathy Questionnaire-Clinical Summary Score (KCCQ-CSS) \< 90 at screening.
6-minute walking distance (6MWD) ≥ 100 m at screening.
Body mass index ≥ 30 to ≤ 50 kg/m2 and Body weight ≤140 kg.
Ability to adhere to study visit schedule and understand and comply with all protocol requirements.

Exclusion Criteria

Hospitalization for any worsening medical condition or major surgery within 4 weeks prior to screening.
Occurrence of an acute coronary syndrome, percutaneous coronary intervention, or cardiac surgery within 90 days prior to Screening.
Implantation of a cardiac resynchronization therapy (CRT) device within 90 days before screening.
Planned cardiovascular revascularization or planned implantation of CRT device.
History of heart transplant or on heart transplant list.
History of serious or life-threatening cardiac arrhythmia within 90 days prior to screening.
Systemic hypotension or uncontrolled systemic hypertension.
History of Pericardial constriction or hypertrophic cardiomyopathy.
History of significant valvular stenosis or regurgitation.
Participants with a pneumonectomy or more than moderate Chronic Obstructive Pulmonary Disease (COPD) or mild interstitial lung disease (ILD) or mild obstructive sleep apnea (OSA).

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Kansas City?

Yes, this clinical trial (NCT07123779) has an active research site in Kansas City, MO that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Pulmonary Hypertension Treatment Options in Kansas City, MO

If you're searching for pulmonary hypertension treatment options in Kansas City, MO, this clinical trial (NCT07123779) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Kansas City research site is actively enrolling participants for this phase 1/2 clinical trial. You'll receive care from experienced pulmonary hypertension specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all pulmonary hypertension clinical trials near you to find additional studies recruiting in your area.

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