Providence, RINCT07132788Now EnrollingIRB Ready

Pulmonary Hypertension Clinical Trial in Providence, RI

Access cutting-edge pulmonary hypertension treatment through this clinical trial at a research site in Providence. Study-provided care at no cost to qualified participants.

Sponsored by University of Pennsylvania

Quick Self-Assessment

See if you qualify for this Providence location

Preparing your pre-screening questions…

Expert Care in Providence

Access pulmonary hypertension specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related pulmonary hypertension treatment provided free

Apply for This Providence Location

Check if you qualify for this pulmonary hypertension clinical trial in Providence, RI

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Providence

    Convenient for RI residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Providence site if eligible
  4. 4Begin participation

About This Pulmonary Hypertension Study in Providence

Patients with pulmonary arterial hypertension (PAH) are at increased risk of muscle loss and decreased physical activity. This study will aim to (1) understand the way in which muscle loss occurs in PAH, particularly the role of fat surrounding the heart, and (2) look at the impact muscle loss has on quality of life, daily physical activity, and hospitalizations in patients with PAH. The findings from this study could help identify potentially treatable factors that may improve the overall quality of life and physical functioning of patients with PAH. Subjects will be asked to attend a baseline visit where the following will be performed: * Measure your vital signs * Undergo a research blood draw, less than 4 tablespoons * Provide a urine pregnancy test (if applicable) * Review demographics, personal history, and medical history * Review current PAH medications * Complete questionnaires on how your PAH affects you * Complete a test of physical performance * Complete a grip strength test * Undergo an echocardiogram (Echo) * Complete a six-minute walk test * Undergo a Chest CT Scan * Undergo a scan of your body composition (DXA scan) * Obtain a weight and body composition measurement on the InBody Scale Subjects will also complete activity moniotring, two 24-hour diet recalls, and participate in remote follow-up visits every 6 months

Sponsor: University of Pennsylvania

Who Can Participate

Inclusion Criteria

Signed informed consent prior to initiation of any study mandated procedure.
Diagnosis of PAH belonging to one of the following subgroups of Group 1 PH according to the updated clinical classification \[Humbert 2022\]
Idiopathic (IPAH)
Heritable (HPAH)
Drugs or toxins induced
Associated (APAH) with one of the following:
Connective tissue disease;
Human immunodeficiency virus (HIV) infection;
Congenital heart disease; or
Portopulmonary hypertension
Diagnosis of PAH within 6 months of enrollment or diagnosis of PAH and on stable therapy for 3 months prior to enrollment
Documented hemodynamic diagnosis of PAH by right heart catheterization (RHC), prior to enrollment showing:
mPAP \> 20 mmHg; and
PAWP or LVEDP ≤ 15 mmHg
PVR \> 2 Wood units

Exclusion Criteria

Prior to enrollment, evidence of moderately severe obstructive ventilator defect with:
FEV1/FVC ≤ 5th percentile; and
FEV1 z-score \< 2.5
Prior to enrollment, evidence of severe restrictive defect with
TLC \< 5th percentile
FEV1 z-score \< 4
Prior to enrollment, hospitalization (within 1 week) for decompensated right heart failure
More than moderate aortic or mitral valve disease
LVEF \< 40% within 1 year of screening

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Providence?

Yes, this clinical trial (NCT07132788) has an active research site in Providence, RI that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Pulmonary Hypertension Treatment Options in Providence, RI

If you're searching for pulmonary hypertension treatment options in Providence, RI, this clinical trial (NCT07132788) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Providence research site is actively enrolling participants for this clinical trial. You'll receive care from experienced pulmonary hypertension specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all pulmonary hypertension clinical trials near you to find additional studies recruiting in your area.

More Hypertension Trials in Providence, RI

See all hypertension clinical trials recruiting in Providence — not just this study.

Browse Hypertension Trials in Providence

Ready to Join in Providence?

Take the first step toward participating in this groundbreaking clinical trial

Secure · Expert Care · Providence, RI