Huntington Beach, CANCT07125729Now EnrollingIRB Ready

Resectable Colorectal Carcinoma Clinical Trial in Huntington Beach, CA

Access cutting-edge resectable colorectal carcinoma treatment through this clinical trial at a research site in Huntington Beach. Study-provided care at no cost to qualified participants.

Sponsored by City of Hope Medical Center

Quick Self-Assessment

See if you qualify for this Huntington Beach location

Preparing your pre-screening questions…

Expert Care in Huntington Beach

Access resectable colorectal carcinoma specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related resectable colorectal carcinoma treatment provided free

Apply for This Huntington Beach Location

Check if you qualify for this resectable colorectal carcinoma clinical trial in Huntington Beach, CA

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Huntington Beach

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Huntington Beach site if eligible
  4. 4Begin participation

About This Resectable Colorectal Carcinoma Study in Huntington Beach

This clinical trial compares minimal residual disease (MRD) testing with the Haystack blood test (assay) to the Signatera® assay for the early detection of the cancer returning (cancer recurrence) in patients with stage II-IV colorectal cancer (CRC) that can be removed by surgery (resectable). MRD testing looks for evidence of remaining tumor following treatment that is only apparent using highly sensitive techniques. There are few effective tools available outside of imaging to identify CRC patients with MRD who may be at the highest risk for cancer recurrence after surgery. Early detection of CRC recurrence after surgery is important, as it may increase the chance of curative (ability to cure) outcomes for patients with cancer recurrence. Currently, the Signatera assay is used to monitor whether CRC recurs after surgery, however it is not a very sensitive test. Early work with the Haystack assay suggests it may be more sensitive than the Signatera assay, which may be more effective for the early detection of cancer recurrence in patients with resectable stage II-IV CRC.

Sponsor: City of Hope Medical Center

Who Can Participate

Inclusion Criteria

Documented written informed consent of the participant
Age: ≥ 18 years
Diagnosis of stage II, III or IV colorectal cancer (any gender) if enrolled post-operatively. If a treatment naïve patient is enrolled pre-operatively and determined to be pathological stage I, the patient will be replaced
Patient who are to undergo a curative intent surgery or have undergone a curative resection and are presenting for surveillance
Patient identified as an appropriate candidate for Signatera® testing as a standard of care MRD surveillance assay
Patient willingness to continue Signatera® assay every 3 months for 2 years in the first 2 years after resection and every 6 months for years 3, 4, 5 after resection, as performed by standard of care testing. In addition, the patients should be willing to provide blood samples for Haystack MRD testing at the same intervals of Signatera®, along with willingness to allow access to archival tissue to allow for Haystack MRD assay personalization. Surveillance with ctDNA should be initiated between 3 to 10 weeks from surgery
Adequate availability of archival tissue or anticipated pathological viable tissue. All untreated primary resection would be expected to have adequate tissue. Patients with resected metastatic disease should have either previously resected primary that is amenable for tumor informed MRD testing or should have adequate archival metastasectomy samples
Patients with total neoadjuvant therapy (TNT) for rectal cancer and complete clinical response with plans of watchful waiting may also be enrolled as long as there is adequate tissue from prior endoscopic biopsies to allow for Signatera® and Haystack MRD assays

Exclusion Criteria

Inability to safely provide sequential blood samples
Clinical evidence of unresected metastatic disease
Inability to give informed consent

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Huntington Beach?

Yes, this clinical trial (NCT07125729) has an active research site in Huntington Beach, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Resectable Colorectal Carcinoma Treatment Options in Huntington Beach, CA

If you're searching for resectable colorectal carcinoma treatment options in Huntington Beach, CA, this clinical trial (NCT07125729) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Huntington Beach research site is actively enrolling participants for this clinical trial. You'll receive care from experienced resectable colorectal carcinoma specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all resectable colorectal carcinoma clinical trials near you to find additional studies recruiting in your area.

More Colorectal Cancer Trials in Huntington Beach, CA

See all colorectal cancer clinical trials recruiting in Huntington Beach — not just this study.

Browse Colorectal Cancer Trials in Huntington Beach →

Browse More Trials by Condition

Colorectal Cancer TrialsAll Conditions →

Ready to Join in Huntington Beach?

Take the first step toward participating in this groundbreaking clinical trial

Secure · Expert Care · Huntington Beach, CA