Boston, MANCT06812052Now EnrollingIRB Ready

Retroperitoneal Sarcoma Clinical Trial in Boston, MA

Access cutting-edge retroperitoneal sarcoma treatment through this clinical trial at a research site in Boston. Study-provided care at no cost to qualified participants.

Sponsored by Brigham and Women's Hospital

Quick Self-Assessment

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Preparing your pre-screening questions…

Expert Care in Boston

Access retroperitoneal sarcoma specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related retroperitoneal sarcoma treatment provided free

Apply for This Boston Location

Check if you qualify for this retroperitoneal sarcoma clinical trial in Boston, MA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Boston

    Convenient for MA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Boston site if eligible
  4. 4Begin participation

About This Retroperitoneal Sarcoma Study in Boston

To determine the safety of moderately hypofractionated radiation in the treatment of primary and locally recurrent RPS, based on the evaluation of acute radiation-related toxicity profile of each participant (30-day radiation toxicity)

Sponsor: Brigham and Women's Hospital

Who Can Participate

Inclusion Criteria

Participants must have a histologically confirmed STS of the retroperitoneal space or infra-peritoneal spaces of pelvis
Participant must have radiologically measurable disease (RECIST 1.1), as confirmed by abdomino-pelvic CT or MRI
Participant must have primary, locally recurrent, or metastatic disease requiring treatment of the retroperitoneal mass
Tumor must be suitable for radiotherapy and surgery based on pre-treatment CT scan/MRI in multidisciplinary discussion with surgeon and radiation oncologist (anticipated macroscopically complete resection, R0/R1 resection)
Age: 18 years or older
ECOG performance status ≤2
Absence of history of bowel obstruction, mesenteric ischemia, or severe chronic inflammatory bowel disease.
Normal renal function (calculated creatinine clearance ≥50 mL/min)
Normal bone marrow and hepatic function (white blood cell count ≥2·5 × 10⁹ cells per L, platelet count ≥80 × 10⁹ cells per L, and total bilirubin \<2 times upper limit of normal)
Women of child-bearing potential must have a negative pregnancy test within 3 weeks prior to the first day of study treatment
Patients capable of childbearing/reproductive potential should use adequate contraception
Ability to understand and the willingness to sign a written informed consent document

Exclusion Criteria

Sarcoma originating from bone structure, abdominal or gynecological viscera
Any of the following histological subtypes: gastrointestinal stromal tumor, rhabdomyosarcoma, primitive neuroectodermal tumor or other small round blue cell sarcoma, osteosarcoma, chondrosarcoma, aggressive fibromatosis, or sarcomatoid or metastatic carcinoma
Prior RT to the RPS
Prior abdominal or pelvic irradiation for other prior malignancy or other disease
Prior different invasive malignancy may be eligible per the discretion of the treating investigator and review by the Principal Investigator (PI)
Prior chemotherapy or immunotherapy within 6 weeks of start of RT
Pregnant women are excluded from this study because RT has the potential for teratogenic or abortifacient effects.
HIV-positive individuals on combination antiretroviral therapy are ineligible because of the potential for increased sensitivity to RT

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Boston?

Yes, this clinical trial (NCT06812052) has an active research site in Boston, MA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Retroperitoneal Sarcoma Treatment Options in Boston, MA

If you're searching for retroperitoneal sarcoma treatment options in Boston, MA, this clinical trial (NCT06812052) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Boston research site is actively enrolling participants for this clinical trial. You'll receive care from experienced retroperitoneal sarcoma specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all retroperitoneal sarcoma clinical trials near you to find additional studies recruiting in your area.

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