Dallas, TXNCT07293871Now EnrollingIRB Ready

Rheumatoid Arthritis Clinical Trial in Dallas, TX

Access cutting-edge rheumatoid arthritis treatment through this clinical trial at a research site in Dallas. Study-provided care at no cost to qualified participants.

Sponsored by Surf Therapeutics

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Expert Care in Dallas

Access rheumatoid arthritis specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related rheumatoid arthritis treatment provided free

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Check if you qualify for this rheumatoid arthritis clinical trial in Dallas, TX

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Dallas

    Convenient for TX residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Dallas site if eligible
  4. 4Begin participation

About This Rheumatoid Arthritis Study in Dallas

This two-stage, multicenter clinical trial is designed to evaluate the feasibility, safety, and preliminary efficacy of splenic ultrasound stimulation to activate immune-neuromodulation (SUSTAIN) in patients with rheumatoid arthritis (RA) and at least moderate disease activity. The findings from this trial will directly inform the design and power calculations for a future pivotal trial by identifying an appropriate effect size and confirming protocol feasibility and safety.

Sponsor: Surf Therapeutics

Who Can Participate

Inclusion Criteria

At least 18 years old
Diagnosis of rheumatoid arthritis as defined by ACR/EULAR 2010 classification criteria
At least moderate disease activity, defined as ≥4 tender joints (28-joint count) and ≥4 swollen joints (28-joint count) and a DAS28-CRP \>3.2 at the baseline visit
hsCRP \> 0.3 mg/dL at the last qualifying visit, baseline or retest
If on background DMARD therapy, must be on stable dose (see

Exclusion Criteria

Able and willing to comply with all study-related procedures, including daily treatment sessions in the study vehicle, research site visits, and assessments Exclusion Criteria:
Unable to provide informed consent
Current or planned participation in another interventional clinical trial
Inflammatory joint disease other than RA (including but not limited to gout, systemic lupus erythematosus, psoriatic arthritis, axial spondyloarthritis including ankylosing spondylitis and non-radiographic axial spondyloarthritis, reactive arthritis, overlap connective tissue diseases, scleroderma, polymyositis, dermatomyositis. Current diagnosis of secondary Sjogren's Syndrome is permitted.
Prior use of \>2 biologic or targeted synthetic DMARDs for RA where the primary reason for discontinuation was efficacy
Conventional synthetic DMARDs:
Initiation within 12 weeks prior to enrollment
Dose adjustment or discontinuation within 4 weeks prior to enrollment
If on a stable dose, inability to maintain the stable dose during the study period
Biologic DMARDs:
Initiation or dose adjustment within 12 weeks prior to enrollment
Discontinuation within 4 weeks prior to enrollment
If on a stable dose, inability to maintain the stable dose during the study period
JAK inhibitors:
Initiation, dose adjustment, or discontinuation within 4 weeks prior to enrollment
If on a stable dose, inability to maintain the stable dose during the study period
Corticosteroids:
Initiation, dose adjustment, or discontinuation within 4 weeks prior to enrollment
Current dose \>10 mg/day prednisone (or equivalent)
If on a stable dose, inability to maintain the stable dose during the study
Initiation, dose adjustment, or discontinuation of high-dose NSAIDs (≥1200 mg/day ibuprofen) within 14 days of informed consent. Over-the-counter use of NSAIDs is permissible.
Pregnant or planning to become pregnant during the study period
Known hypersensitivity to ultrasound gel or membrane components
History of splenic disorders, including splenectomy, congenital asplenia, or splenomegaly on baseline visit ultrasound
Rash, wound, or skin infection overlying the spleen
History of vagal nerve injury, vagotomy, or known autonomic neuropathy
Recent abdominal surgery or trauma within 30 days of screening
Skin to spleen hilum depth \>7 cm as measured by ultrasound at the baseline visit
Abdominal anatomy or condition precluding adequate ultrasound targeting of the spleen
Uncontrolled fibromyalgia or other diffuse pain syndromes that may confound symptom reporting
Any condition that, in the investigator's judgment, would preclude safe participation or compliance with study procedures

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Dallas?

Yes, this clinical trial (NCT07293871) has an active research site in Dallas, TX that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Rheumatoid Arthritis Treatment Options in Dallas, TX

If you're searching for rheumatoid arthritis treatment options in Dallas, TX, this clinical trial (NCT07293871) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Dallas research site is actively enrolling participants for this clinical trial. You'll receive care from experienced rheumatoid arthritis specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all rheumatoid arthritis clinical trials near you to find additional studies recruiting in your area.

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