Baltimore, MDNCT03971669Now EnrollingIRB Ready

Risk Reduction Clinical Trial in Baltimore, MD

Access cutting-edge risk reduction treatment through this phase 4 clinical trial at a research site in Baltimore. Study-provided care at no cost to qualified participants.

Sponsored by University of Maryland, Baltimore

Quick Self-Assessment

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Expert Care in Baltimore

Access risk reduction specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related risk reduction treatment provided free

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Check if you qualify for this risk reduction clinical trial in Baltimore, MD

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Baltimore

    Convenient for MD residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Baltimore site if eligible
  4. 4Begin participation

About This Risk Reduction Study in Baltimore

This is an open-label, non-randomized study. Volunteers will be vaccinated with the typhoid oral vaccine, Vivotif. Vivotif has been licensed by the Food and Drug Administration (FDA) for travelers to developing countries. Volunteers will also be asked to provide blood, saliva, and stool specimens over a follow-up time period of up to eight years. The specimens obtained in this clinical research study will be used to further the investigator's understanding of the protective immunological mechanisms that can be elicited systemically and may be applicable to other enteric pathogens.

Sponsor: University of Maryland, Baltimore

Who Can Participate

Inclusion Criteria

Age 18 years and older
Good general health as determined by a screening evaluation within 28 days before blood donation
Informed, written consent

Exclusion Criteria

History of any of the following medical illnesses:
Cancer in past 5 years (except for basal cell carcinoma of the skin and cervical carcinoma in situ)
Heart disease (Hospitalization for a heart attack, coronary artery bypass graft, arrhythmia, or syncope, within past 5 years. Current symptoms of heart disease - dyspnea, angina, orthopnea)
Recurrent infections (more than 3 hospitalizations for invasive bacterial infections such as pneumonia or meningitis)
Current drug or alcohol abuse
Active ulcer disease or ongoing intestinal condition
Treatment for anemia in last 6 months
Currently being treated with anti-malarial drugs
Any of the following laboratory abnormalities detected during medical screening:
WBC \<0.81 x LLN or \> 1.09 x ULN
Hemoglobin \<0.91 x LLN or \>1.18 x ULN (women) or \<0.92 x LLN or \>1.18 x ULN (men)
Platelet count \<0.8 x LLN or \> 1.2 x ULN
(For leukopheresis or blood unit donations, the following lab values are exclusionary:
WBC \<3.5 or \>11 x 103/mm3;
Hemoglobin \<12.5 or \>18 g/dl
Platelet count \<150 or \>500 x 103/mm3)
SGOT or SGPT \>1.5 times normal
Positive serology for hepatitis C or HIV antibody or hepatitis B surface antigen
Positive serology for hepatitis B core antibody
Poor peripheral venous access for blood donation
Positive RPR
Other condition that in the opinion of the investigator would jeopardize the safety or rights of a volunteer participating in the trial or interfere with the scientific integrity of study.
Positive urine pregnancy test (HCG) on day of vaccination. Prior to each blood donation -females with menstrual history consistent with pregnancy. Pregnant women will not be enrolled, because immunological changes that occur during pregnancy may interfere with laboratory assays.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Baltimore?

Yes, this clinical trial (NCT03971669) has an active research site in Baltimore, MD that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Risk Reduction Treatment Options in Baltimore, MD

If you're searching for risk reduction treatment options in Baltimore, MD, this clinical trial (NCT03971669) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Baltimore research site is actively enrolling participants for this phase 4 clinical trial. You'll receive care from experienced risk reduction specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all risk reduction clinical trials near you to find additional studies recruiting in your area.

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