Houston, TXNCT03971487Now EnrollingIRB Ready

Schizo-Affective Type of Psychosis Clinical Trial in Houston, TX

Access cutting-edge schizo-affective type of psychosis treatment through this clinical trial at a research site in Houston. Study-provided care at no cost to qualified participants.

Sponsored by The Methodist Hospital Research Institute

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Expert Care in Houston

Access schizo-affective type of psychosis specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related schizo-affective type of psychosis treatment provided free

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Check if you qualify for this schizo-affective type of psychosis clinical trial in Houston, TX

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Why Participate?

  • No-Cost Study Care

  • Local to Houston

    Convenient for TX residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Houston site if eligible
  4. 4Begin participation

About This Schizo-Affective Type of Psychosis Study in Houston

Some people who have what doctors currently call schizophrenia or bipolar disease may actually have a brain disease caused by auto-antibodies. Auto-antibodies are produced when the normal defense mechanism of the body goes wrong and begins to attack the body, similar to "friendly fire." Auto-antibodies attack brain receptors and then the person who has this problem begins to have hallucinations and other manifestations of schizophrenia, like feeling that people can see what they are thinking and also feeling that other people do not like them. If this disease is caused by auto-antibodies, typically the person is well until they are 15 years of age or older, but seldom older than 35 years. Then, in a matter of a few months they begin to have hallucinations and the other symptoms. Doctors still do not know whether some people with schizophrenia or bipolar disease have auto-antibodies attacking their brain. For this reason, in this study some of these patients will receive a treatment that suppresses the auto-antibodies and their symptoms after treatment will be compared with the symptoms of a group of similar patients who are given a preparation that looks like the real treatment, but it is not.

Sponsor: The Methodist Hospital Research Institute

Who Can Participate

Inclusion Criteria

Individuals of either sex, 18-35 years of age.
Having an active psychotic disorder meeting DSM-5 criteria, including a duration of at least six months, for Schizophrenia Spectrum Disorder, as defined by the Mini International Neuropsychiatric Interview (MINI).
A total PANSS ≥ 60 and a score ≥ 4 on at least 2 of the PANSS positive symptoms.
Normal academic performance at least until the age of 15 years and absence of psychiatric symptoms before the same age.
Ability to assent or consent to the performance of the study and participate in testing procedures.

Exclusion Criteria

The dose of antipsychotic medication (if they are on one) has been changed less than two weeks prior to baseline PANSS testing (Visit 2, see below).
Patient treated with a medication designed to suppress the immune system, other than standard analgesics or antipyretics, in the six months prior to randomization.
Vaccinated with a live-attenuated vaccine less than 4 weeks before ocrelizumab infusion or with a non-live vaccine less than 2 weeks before infusion.
Active infection, or history of or known presence of recurrent or chronic infection (for example, hepatitis B or C, Human Immunodeficiency Virus, syphilis, tuberculosis, PML).
History of brain tumor, stroke, severe head trauma or multiple sclerosis.
Active cancer, metabolic encephalopathy, severe cardiovascular or renal disease.
In the judgment of the PI, psychosis related to substance abuse or metabolic disorders.
Pregnancy or lactation.
Requirement for chronic treatment with systemic corticosteroids or immunosuppressants during the course of the study.
History of or currently active primary or secondary immunodeficiency.
History of severe allergic or anaphylactic reactions to humanized or murine monoclonal antibodies.
Contraindications to or intolerance of oral or IV corticosteroids.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Houston?

Yes, this clinical trial (NCT03971487) has an active research site in Houston, TX that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Schizo-Affective Type of Psychosis Treatment Options in Houston, TX

If you're searching for schizo-affective type of psychosis treatment options in Houston, TX, this clinical trial (NCT03971487) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Houston research site is actively enrolling participants for this clinical trial. You'll receive care from experienced schizo-affective type of psychosis specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all schizo-affective type of psychosis clinical trials near you to find additional studies recruiting in your area.

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