Gainesville, FLNCT05110937Now EnrollingIRB Ready

Sepsis Clinical Trial in Gainesville, FL

Access cutting-edge sepsis treatment through this clinical trial at a research site in Gainesville. Study-provided care at no cost to qualified participants.

Sponsored by University of Florida

Quick Self-Assessment

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Expert Care in Gainesville

Access sepsis specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related sepsis treatment provided free

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Check if you qualify for this sepsis clinical trial in Gainesville, FL

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Gainesville

    Convenient for FL residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Gainesville site if eligible
  4. 4Begin participation

About This Sepsis Study in Gainesville

Adverse outcomes in surgical sepsis patients are secondary to dysregulated emergency myelopoiesis, and expansion of myeloid-derived suppressor cells. Here we propose to determine the underlying mechanisms behind the increased expansion of these leukocyte populations and the underlying mechanisms that drive inflammation and immune suppression.

Sponsor: University of Florida

Who Can Participate

Inclusion Criteria

age ≥18 years
meets criteria for sepsis/septic shock by Sepsis-3 consensus criteria.

Exclusion Criteria

have disease states that predispose to significant immune system dysfunction
have comorbidity burden or goals of care that preclude recovery after sepsis. These criteria include: a. irreversible shock (death \<12 hours) b. uncontrollable surgical source of sepsis c. patients deemed to be futile care or have advanced directives limiting resuscitative efforts d. alternative diagnoses causing shock state (e.g., hemorrhage, myocardial infarction or pulmonary embolus) e. known HIV infection with CD4+ count \<200 cells/mm3 g. severe traumatic brain injury with unencumbered assessment of GCS equaling 3 on admission to the intensive care unit.
known pregnancy
enrollment \>96 hours after suspected sepsis onset
pre-hospitalization bedridden performance status (WHO/Zubrod score ≥4)
subsequent clinical adjudication diagnosis not consistent with sepsis/septic shock by Sepsis-3 criteria.
Burn injury greater than 20% total body surface area (tBSA) Trauma Participant: Inclusion Criteria
All adults age ≥ 18 years
Blunt trauma patient with a. Injury Severity Score (ISS) greater than or equal to 25 b. ISS \> 15 and one of the following: i. \> 4 units of PRBC or \>3 units of whole blood or \>1500 ml of autogenous blood product in the first 24 hours of admission ii. AIS (acute injury score) \> 2 spine iii. Shock on arrival (Systolic blood pressure (SBP) \< 90) OR c. ISS \> 15 and two of the following: i. Age \> 55 ii. AIS \> 2 chest iii. +ETOH (ethyl alcohol) on arrival iv. Any red blood cell transfusion in first 24 hours Exclusion Criteria
Patients not expected to survive greater than 48 hours.
Previous bone marrow transplantation.
Patients with End Stage Renal Disease.
Patients with any pre-existing hematological disease.
Patients deemed to be futile care or have advanced directives limiting resuscitative efforts.
Known HIV infection with CD4+ count \<200 cells/mm3
Burn injury greater than 20% tBSA

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Gainesville?

Yes, this clinical trial (NCT05110937) has an active research site in Gainesville, FL that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Sepsis Treatment Options in Gainesville, FL

If you're searching for sepsis treatment options in Gainesville, FL, this clinical trial (NCT05110937) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Gainesville research site is actively enrolling participants for this clinical trial. You'll receive care from experienced sepsis specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all sepsis clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Gainesville, FL