Eau Claire, WINCT06319248Now EnrollingIRB Ready

Sepsis Clinical Trial in Eau Claire, WI

Access cutting-edge sepsis treatment through this clinical trial at a research site in Eau Claire. Study-provided care at no cost to qualified participants.

Sponsored by Mayo Clinic

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Expert Care in Eau Claire

Access sepsis specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related sepsis treatment provided free

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Check if you qualify for this sepsis clinical trial in Eau Claire, WI

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Eau Claire

    Convenient for WI residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Eau Claire site if eligible
  4. 4Begin participation

About This Sepsis Study in Eau Claire

This study is being done to determine if early administration of Midodrine can improve outcomes by maintaining a higher mean blood pressure off of intravenous medications. Researchers want to see if Midodrine can help people with sepsis need fewer vasopressors, which could mean shorter hospital stays, less time with uncomfortable tubes, and a smoother recovery overall.

Sponsor: Mayo Clinic

Who Can Participate

Inclusion Criteria

Patients diagnosed with sepsis within 24 hours of meeting all of the following criteria will be eligible to participate in the study:
Sepsis-3 criteria: acute hospital admission for suspected infection with new or worsening organ dysfunction measured by the increase in Sequential Organ failure Assessment (SOFA) score of 2 points or more.
IV vasopressor use or persistent hypotension (MAP \< 65 mm Hg) after initial fluid resuscitation in the ED or ICU (30 mL/kg unless deemed excessive by the treating clinician).

Exclusion Criteria

High-dose vasopressors (norepinephrine equivalent \> 0.3 μg/kg/min)
Inadequately controlled source of infection
Cardiogenic or obstructive (massive pulmonary embolism) shock
Clinical suspicion or confirmed diagnosis of bowel obstruction, bowel ischemia, or ileus
Contraindication to enteral intake (ileus, vomiting, gastrointestinal bleeding, endoscopic procedures etc.)
Recent myocardial infarction (STEMI or NSTEMI Type 1 within the past 3 months)
Recent treatment for peripheral vascular disease (within the past 3 months) or acute limb ischemia
Current use of monoamine oxidase inhibitors
Recent stroke (within the past 3 months)
Prior use of midodrine as a home medication
Known allergy to midodrine
Comfort care measures
Bradycardia (heart rate \< 50 beats/min)
Untreated pheochromocytoma
Untreated thyrotoxicosis
Acute Angle-Closure Glaucoma
Cirrhosis or liver failure with Child-Pugh Score \> 12
Venous blood lactate \> 4
Treating emergency or critical care physician unwilling to enroll patient in trial
Inability to give consent for participation and no representative or surrogate available to consent

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Eau Claire?

Yes, this clinical trial (NCT06319248) has an active research site in Eau Claire, WI that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Sepsis Treatment Options in Eau Claire, WI

If you're searching for sepsis treatment options in Eau Claire, WI, this clinical trial (NCT06319248) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Eau Claire research site is actively enrolling participants for this clinical trial. You'll receive care from experienced sepsis specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all sepsis clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Eau Claire, WI