Durham, NCNCT07139899Now EnrollingIRB Ready

Severe Asthma Clinical Trial in Durham, NC

Access cutting-edge severe asthma treatment through this clinical trial at a research site in Durham. Study-provided care at no cost to qualified participants.

Sponsored by Bastiaan Driehuys

Quick Self-Assessment

See if you qualify for this Durham location

Preparing your pre-screening questions…

Expert Care in Durham

Access severe asthma specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related severe asthma treatment provided free

Apply for This Durham Location

Check if you qualify for this severe asthma clinical trial in Durham, NC

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Durham

    Convenient for NC residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Durham site if eligible
  4. 4Begin participation

About This Severe Asthma Study in Durham

In this study, xenon MRI will be used to evaluate regional functional consequences of mucus plugs in the lungs of patients with severe asthma. Mucus plugs will be identified using CT imaging, and xenon MRI will be used to evaluate ventilation and gas exchange impairments in regions of the lungs corresponding to the airways downstream of mucus plugs.

Sponsor: Bastiaan Driehuys

Who Can Participate

Inclusion Criteria

Adequate completion of informed consent process with written documentation
Patients 18 - 65 years old
Physician diagnosis of asthma for \> 1 year
Able to perform reproducible spirometry according to ATS criteria based on clinical PFTs within previous 30 days of enrollment
All racial/ethnic backgrounds may participate
Blood eosinophil count \> 300 cells/μL
Smoking history \<10 pack years
No smoking history (including vapes, cigar, or marijuana use) in the last 3 months
About to initiate asthma therapy with either dupilumab, tezepelumab, or benralizumab as part of their standard of care

Exclusion Criteria

Respiratory tract infection within the 4 weeks prior to Visit 1
Body mass index (BMI) \> 30 at Visit 1
One-time doses such as intra-articular injections require a 4-week washout prior to Visit 1
Asthma-related ER visit within the previous 4 weeks of Visit 1 or at any time while on the study
Significant concomitant medical illness, including (but not limited to) heart disease, cancer, uncontrolled diabetes, other chronic lung diseases (determined by the Investigator.)
Resting O2 saturation \<90% with maximum supplemental O2 delivered by nasal cannula
Positive urine pregnancy test at Visit 1 or at any time while on the study
Participation in an intervention study (including bronchoscopy) or use of investigative drugs within the past 30 days or plans to enroll in such a trial during the study
Unable or unlikely to complete study assessments in the opinion of the Investigator
Study intervention poses undue risk to patient in the opinion of the Investigator
Conditions that will prohibit MRI scanning determined by the MRI safety screening.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Durham?

Yes, this clinical trial (NCT07139899) has an active research site in Durham, NC that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Severe Asthma Treatment Options in Durham, NC

If you're searching for severe asthma treatment options in Durham, NC, this clinical trial (NCT07139899) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Durham research site is actively enrolling participants for this clinical trial. You'll receive care from experienced severe asthma specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all severe asthma clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Durham, NC