Washington Dc, DCNCT06635902Now EnrollingIRB Ready

Sickle Cell Disease Clinical Trial in Washington Dc, DC

Access cutting-edge sickle cell disease treatment through this phase 2 clinical trial at a research site in Washington Dc. Study-provided care at no cost to qualified participants.

Sponsored by Suvankar Majumdar

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Expert Care in Washington Dc

Access sickle cell disease specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related sickle cell disease treatment provided free

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Why Participate?

  • No-Cost Study Care

  • Local to Washington Dc

    Convenient for DC residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Washington Dc site if eligible
  4. 4Begin participation

About This Sickle Cell Disease Study in Washington Dc

The goal of this clinical trial is to learn if intravenous citrulline works to treat acute pain in hospitalized patients with sickle cell disease. It will also learn about the safety of intravenous citrulline. The main questions it aims to answer are: * Does intravenous citrulline decrease the duration of sickle cell pain during hospitalization * What medical problems do participants have when taking intravenous citrulline? Researchers will compare intravenous citrulline to a placebo (a look-alike substance that contains no drug) to see if intravenous citrulline works to treat acute pain. Participants will: * Receive baseline tests and intravenous citrulline for 16 hours during the hospital stay * After hospital discharge, visit the clinic in about 30 days for checkup and tests

Sponsor: Suvankar Majumdar

Who Can Participate

Inclusion Criteria

Sickle cell disease (all genotypes)
Patients with sickle cell disease ages 4 to 21 years old
Presence of sickle cell vaso-occlusive pain episode requiring hospitalization and parenteral opioid therapy
Able to randomize to study drug/placebo within 12 hours of first dose of parenteral opioid in the Emergency Department

Exclusion Criteria

Current pain lasting \>3 days.
\>9 hospitalizations in the prior year
Presence of any other complication related to sickle cell disease requiring the hospitalization such as splenic sequestration, hepatic sequestration, stroke, transient ischemic attack, etc.
History of opioid use disorder, chronic pain or medical regimen requiring daily opioid use.
Severe anemia (hemoglobin \<6g/dL)
Pregnant (as confirmed by a positive urine pregnancy test) or lactating female.
Alanine/aspartate transferase \>2x upper limit of normal laboratory range for age.
Subject has the following serum creatinine:
Age 4 to 13 years \> 0.9 mg/dL
Age 14 to 17 years 1.0 mg/dL
Age ≥18 years \>1.5mg/dL
Presence of acute chest syndrome, sepsis, bacterial infection, hemodynamic instability
Use of L-glutamine
History of allergic reaction to L-citrulline products

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Washington Dc?

Yes, this clinical trial (NCT06635902) has an active research site in Washington Dc, DC that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Sickle Cell Disease Treatment Options in Washington Dc, DC

If you're searching for sickle cell disease treatment options in Washington Dc, DC, this clinical trial (NCT06635902) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Washington Dc research site is actively enrolling participants for this phase 2 clinical trial. You'll receive care from experienced sickle cell disease specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all sickle cell disease clinical trials near you to find additional studies recruiting in your area.

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