Portland, ORNCT06721884Now EnrollingIRB Ready

Small Intestinal Bacterial Overgrowth Syndrome (SIBO) Clinical Trial in Portland, OR

Access cutting-edge small intestinal bacterial overgrowth syndrome (sibo) treatment through this clinical trial at a research site in Portland. Study-provided care at no cost to qualified participants.

Sponsored by National University of Natural Medicine

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Expert Care in Portland

Access small intestinal bacterial overgrowth syndrome (sibo) specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related small intestinal bacterial overgrowth syndrome (sibo) treatment provided free

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Check if you qualify for this small intestinal bacterial overgrowth syndrome (sibo) clinical trial in Portland, OR

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Why Participate?

  • No-Cost Study Care

  • Local to Portland

    Convenient for OR residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Portland site if eligible
  4. 4Begin participation

About This Small Intestinal Bacterial Overgrowth Syndrome (SIBO) Study in Portland

Small intestinal bacterial overgrowth (SIBO) can cause symptoms like bloating, stomach pain, and changes in bowel movements, significantly affecting quality of life. Many people with irritable bowel syndrome (IBS) also have SIBO, and there is growing recognition of how important it is to address this condition. Artemisia annua has shown potential in managing SIBO based on early reports and studies suggesting it can fight bacteria like \*E. coli\* and \*Klebsiella\*, which are linked to a type of SIBO that produces hydrogen gas. This study aims to test if Artemisia annua is safe and well-tolerated for adults with hydrogen-type SIBO. Over five weeks, participants will take either 5 grams of dried Artemisia annua leaves or a placebo. Researchers will monitor safety through blood tests, vital signs, and adverse events, and they will assess symptom changes using questionnaires and breath tests. The trial will include up to 32 participants from the Portland, Oregon area. Participants will be randomly assigned to treatment groups, and neither they, the researchers, nor the test administrators will know who is receiving the herb or the placebo. Results will be analyzed using standard statistical methods. This study addresses the lack of research on herbal treatments for SIBO. If successful, the findings could lead to larger studies and help expand treatment options for people with SIBO.

Sponsor: National University of Natural Medicine

Who Can Participate

Inclusion Criteria

Adults 18 years of age or older
IBS-SSS score \>175
Meets North American Consensus criteria for H2 SIBO
Willing to take Artecinua™ or placebo as a dietary supplement for 5 weeks
Willing to have two lactulose breath tests and do the prep diet 24 hours before and fast overnight before the test
Willing to have three blood drawstests and fast overnight before the draw
Able to speak, read, and understand English
Able to provide informed consent
For individuals of child-bearing potential, willing to use an intrauterine device or two other concurrent forms of birth control to prevent pregnancy while enrolled

Exclusion Criteria

Use of antibiotic pharmaceuticals or supplements 14 days before baseline breath test
Initiation of change in diet, medication, or supplement regime within 30 days
Hospitalization within the past 3 months
Women who are breastfeeding, pregnant, or planning pregnancy in the next 4 months
Allergies to any of the ingredients in the study products.
Individuals with chronic kidney or liver disease, cancer, colorectal disease and/or other rare disorders that at the discretion of the PI or Clinical \*Investigator may impact their safety or confound trial results
The use of any high-risk medications with narrow therapeutic indices metabolized by CYP450 enzymes: Warfarin (CYP2C9), Tacrolimus/Cyclosporine (CYP3A4), Efavirenz (CYP2B6), and Codeine (CYP2D6).
Drugs requiring activation for efficacy: Clopidogrel (CYP2C19), Codeine (CYP2D6), and Tamoxifen (CYP2D6) (citations).
GFR: \<30 mL/min/1.73m²
Hepatitis from any cause.
Excessive alcohol use (\> seven drinks/week in women and \> fourteen in men).
Hepatic (ALT, AST, bilirubin) and renal (creatinine, estimated GFR) parameters outside of normal range at screening.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Portland?

Yes, this clinical trial (NCT06721884) has an active research site in Portland, OR that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Small Intestinal Bacterial Overgrowth Syndrome (SIBO) Treatment Options in Portland, OR

If you're searching for small intestinal bacterial overgrowth syndrome (sibo) treatment options in Portland, OR, this clinical trial (NCT06721884) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Portland research site is actively enrolling participants for this clinical trial. You'll receive care from experienced small intestinal bacterial overgrowth syndrome (sibo) specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all small intestinal bacterial overgrowth syndrome (sibo) clinical trials near you to find additional studies recruiting in your area.

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