NCT05973461 · The University of Texas at Arlington
Effects of Exercise and Virtual Reality on Depression
What this study is about
This study is evaluating the effects of riding on a cycle ergometer while experiencing virtual reality to determine its effect on mood.
View original scientific description
This study is evaluating the effects of riding on a cycle ergometer while experiencing virtual reality to determine its effect on mood.
Interventions
DEVICE
Exercise and virtual reality
Riding a cycle ergometer while experiencing virtual reality
OTHER
Riding a cycle ergometer
Riding on a cycle ergometer without experiencing virtual reality
Primary outcome measures
Beck Depression Inventory Scale of Measurement
Time frame: 5 minutes
Assessment of symptoms of depression pre and post-intervention cycle exercise. The Beck Depression Inventory is a 21-item, multiple-choice, self-report survey that measures characteristic attitudes and symptoms of depression. The score range is 0-63. The higher the score the more severe the depression. Scores above 41 are considered "extreme depression."
Spatial Working Memory (SWM)
Time frame: 8 minutes
A measure of the key aspects of working memory and storage of information over short periods of time.
Neuropsychological Outcomes: Motor Screen Tasks (MOT)
Time frame: 3 minutes
MOT provides a general indication that psychomotor function is intact enough to proceed with more sophisticated cognitive testing:
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- Males and females over the age of 18 years
- With or without symptoms of depression
- Physically inactive or sedentary (less than 30 minutes per day)
- Normal vision and no color blindness
- No physical disorders such as walking with assistance
Exclusion criteria
- Below the age of 18 years or over 65 years,
- Women who are pregnant
- Individuals who have been diagnosed with mental disorders
- Individuals with leg injuries
- Individuals with cardiac problems
- Individuals with a history of asthma
- Individuals with a body mass index over 30.
Where
- Arlington, Texas
Related conditions & keywords
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced May 29, 2026 · Source of record for eligibility and locations