Rochester, MNNCT07483177Now EnrollingIRB Ready

Thoracic Aortic Aneurysm Clinical Trial in Rochester, MN

Access cutting-edge thoracic aortic aneurysm treatment through this clinical trial at a research site in Rochester. Study-provided care at no cost to qualified participants.

Sponsored by Mayo Clinic

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Expert Care in Rochester

Access thoracic aortic aneurysm specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related thoracic aortic aneurysm treatment provided free

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Check if you qualify for this thoracic aortic aneurysm clinical trial in Rochester, MN

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Rochester

    Convenient for MN residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Rochester site if eligible
  4. 4Begin participation

About This Thoracic Aortic Aneurysm Study in Rochester

The purpose of this study is to determine whether spironolactone reduces aortic stiffness, measured by carotid-femoral pulse wave velocity (cfPWV), compared with placebo, in patients with degenerative thoracic aortic aneurysms.

Sponsor: Mayo Clinic

Who Can Participate

Inclusion Criteria

Adults ≥ 18 years old with dTAA of the aortic root and/or ascending aorta exceeding the upper limit of normal for age, sex, and body surface area (≥ 4.0 cm as an example of a common threshold; but age, sex and body size-specific thresholds have been established for the aortic root24 and ascending aorta25);
no antihypertensive use or stable antihypertensive regimen ≥ 4 weeks;
eGFR ≥ 50 mL/min/1.73 m²;
serum potassium ≤ 5.1 mmol/L;
ability to provide informed consent.

Exclusion Criteria

Heritable aortopathies (Marfan, Loeys-Dietz, vascular Ehlers-Danlos, Turner syndromes; familial TAA, genetically-proven TAA);
bicuspid aortic valve;
inflammatory aortitis,
prior aortic surgery, endovascular repair, or acute aortic syndrome;
permanent atrial fibrillation/flutter;
major peripheral artery disease affecting the carotids, iliacs and/or external femoral arteries precluding cfPWV measurement;
current use of spironolactone, eplerenone or finererone;
pregnancy or lactation.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Rochester?

Yes, this clinical trial (NCT07483177) has an active research site in Rochester, MN that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Thoracic Aortic Aneurysm Treatment Options in Rochester, MN

If you're searching for thoracic aortic aneurysm treatment options in Rochester, MN, this clinical trial (NCT07483177) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Rochester research site is actively enrolling participants for this clinical trial. You'll receive care from experienced thoracic aortic aneurysm specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all thoracic aortic aneurysm clinical trials near you to find additional studies recruiting in your area.

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