Columbus, OHNCT02860364Now EnrollingIRB Ready

Thoracic Aortic Disease Clinical Trial in Columbus, OH

Access cutting-edge thoracic aortic disease treatment through this clinical trial at a research site in Columbus. Study-provided care at no cost to qualified participants.

Sponsored by Ottawa Heart Institute Research Corporation

Quick Self-Assessment

See if you qualify for this Columbus location

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Expert Care in Columbus

Access thoracic aortic disease specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related thoracic aortic disease treatment provided free

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Check if you qualify for this thoracic aortic disease clinical trial in Columbus, OH

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Columbus

    Convenient for OH residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Columbus site if eligible
  4. 4Begin participation

About This Thoracic Aortic Disease Study in Columbus

Hypothermic circulatory arrest is an important surgical technique, allowing complex aortic surgeries to be performed safely. Hypothermic circulatory arrest provides protection to cerebral and visceral organs, but may result in longer cardiopulmonary bypass times during surgery, increased risks of bleeding, inflammation, and neuronal injury. To manage these consequences, a trend towards warmer core body temperatures during circulatory arrest has emerged. This trial will randomize patients to either mild (32°C) or moderate (26°C) hypothermia during aortic hemiarch surgery to determine if mild hypothermia reduces the length of cardiopulmonary bypass time and other key measures of morbidity and mortality.

Sponsor: Ottawa Heart Institute Research Corporation

Who Can Participate

Inclusion Criteria

Age ≥ 18 years
Elective aortic hemiarch surgery
Planned unilateral selective anterograde cardioplegia
Anticipated lower body arrest time of \< 20 minutes
Able to provide written informed consent

Exclusion Criteria

Surgery for acute aortic dissection or emergent operations
Total arch replacement
Inability to perform unilateral selective anterograde cerebral perfusion (uSACP)
Patients with known/documented coagulopathy
Patients with cold agglutinin disease or those that test positive on routine preop screening
Pre-existing severe neurological impairment or inability to accurately assess neurocognitive function as determined by the operating surgeon
Severe carotid disease, defined as: any patient with previously documented carotid stenosis of \> 70% (via Doppler ultrasound (US), magnetic resonance angiography (MRA), or computer tomography angiography (CTA)) without neurological deficits; or carotid stenosis \> 50% with neurological deficits; or previous carotid endarterectomy or stenting
Patients in renal failure or currently being treated with renal replacement therapy (RRT) or estimated glomerular filtration rate (eGFR) \< 30 ml/min/1.73m2
Use of an investigational drug or device at time of enrollment
Participation in another clinical trial which interferes with performance of the study procedures or assessment of the outcomes

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Columbus?

Yes, this clinical trial (NCT02860364) has an active research site in Columbus, OH that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Thoracic Aortic Disease Treatment Options in Columbus, OH

If you're searching for thoracic aortic disease treatment options in Columbus, OH, this clinical trial (NCT02860364) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Columbus research site is actively enrolling participants for this clinical trial. You'll receive care from experienced thoracic aortic disease specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all thoracic aortic disease clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Columbus, OH