NCT07049757 · University of California, San Francisco
Healthy Family Project: Tobacco Use and Smoke Exposure in Asian American Communities
What this study is about
This study evaluates whether the Smokefree Family Living (SFL) intervention improves quit rates (smoking cessation) and exposure to tobacco contamination that stays in items such as, carpets, walls, and furniture, even after the smoke has cleared (third-hand smoke (THS)) among Chinese American smokers and their non-smoking household members.
View original scientific description
This study evaluates whether the Smokefree Family Living (SFL) intervention improves quit rates (smoking cessation) and exposure to tobacco contamination that stays in items such as, carpets, walls, and furniture, even after the smoke has cleared (third-hand smoke (THS)) among Chinese American smokers and their non-smoking household members. Smoking remains high among Chinese American males with limited ability to speak English. This causes the non-smoking household members to be exposed to THS, which contains many of the same harmful components as smoking and becomes more toxic as it ages. SFL is tailored for Chinese Americans and combines the contents of the Quit Smoking for a Healthy Family (QS) intervention with additional THS education and cleaning strategies. QS focuses on smoking cessation through educational sessions and support. THS education and cleaning strategies provide information on THS and how to clean the home for THS.
Interventions
OTHER
Smoking cessation education
Quit Smoking for a Healthy Family (QS) and Smokefree Family Living (SFL) education sessions to promote smoking cessation and reduce tobacco smoke exposure.
BEHAVIORAL
Survey Administration
Administered for ancillary studies
BEHAVIORAL
Telephone-Based Intervention
Participants will receive follow-up calls
PROCEDURE
Urine Specimen Collection
Undergo urine sample collection at baseline
OTHER
Silicone Wrist Band
Non-smoking family/household members will wear a silicone wristband for 2 days at each assessment for ancillary studies
OTHER
Interview
Selected participants will take part in an interview for ancillary studies
OTHER
Focus Group
Participants will review and comment on materials under development to be used in randomized clinical trial.
Primary outcome measures
Proportion of participants who have quit smoking at 6 months
Time frame: 6 months
The smoking cessation rate is defined as the proportion of smokers who report quitting smoking, with biochemically verified 30-day point prevalent abstinence at the 6-month follow-up. Smoking rates will be reported by arm.
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- All Participants (Lay Health Workers, Smokers, Family Participants, and Post-Trial Household Member Group Interview Participants):
- Must be 18 years of age or older.
- Must self-identify as Chinese or of Chinese descent (ethnic or cultural identification, not national origin).
- Must be able to understand in spoken Chinese (Cantonese and/or Mandarin) or English.
- Able to attend educational sessions in person or via video conferencing.
- Ability to understand and the willingness to sign a written informed consent document.
- Have a mobile phone that can receive Short Message Service (SMS) text messages, or an email address and a phone number where they can be reached by the study team. Lay Health Workers:
- Must have experience or interest in community outreach and education.
- Must demonstrate proficiency in language (Cantonese and/or Mandarin or English) sufficient to deliver study materials and interact with participants.
- Must be affiliated with the Chinese Community Health Resource Center (CCHRC) or recruited through community networks.
- Must agree to participate in training and intervention delivery activities as outlined in the study protocol. Smokers (Participants who are current smokers):
- Must have smoked within the past 30 days, either daily or occasionally.
- Must have a non-smoking household member. Family Participants (Non-smoking family/household members):
- Must live in the same household as the smoker participant.
- Must not have used any tobacco products in the past 30 days. Post-Trial Household Member Group Interview Participants: 1\. Living in the same household with the smoker-household member dyad participant being interviewed or considered as a household member.
Exclusion criteria
- Lay Health Workers, Smokers (Participants who are current smokers) and Family Participants (Non-smoking Family/household members):
- Currently participating in another smoking cessation program.
- Non-residents of California.
- Participants unwilling to provide follow-up contact for assessments at 6 and 12 months. Lay Health Workers:
- Lack of willingness or ability to complete training or deliver intervention sessions as required by the study protocol.
- Inability to maintain confidentiality and professionalism during interactions with study participants.
- Active participation in conflicting research studies or programs.
Where
- San Francisco, California
Collaborators
Tobacco Related Disease Research Program
Related conditions & keywords
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Jun 4, 2026 · Source of record for eligibility and locations