Houston, TXNCT06640491Now EnrollingIRB Ready

Total Knee Arthroplasty Clinical Trial in Houston, TX

Access cutting-edge total knee arthroplasty treatment through this phase 1/2 clinical trial at a research site in Houston. Study-provided care at no cost to qualified participants.

Sponsored by The Methodist Hospital Research Institute

Quick Self-Assessment

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Preparing your pre-screening questions…

Expert Care in Houston

Access total knee arthroplasty specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related total knee arthroplasty treatment provided free

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Check if you qualify for this total knee arthroplasty clinical trial in Houston, TX

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Houston

    Convenient for TX residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Houston site if eligible
  4. 4Begin participation

About This Total Knee Arthroplasty Study in Houston

The goal of this clinical trial is to compare the efficacy of intravenous (IV) and intraosseous (IO) antibiotic administration techniques during primary total knee arthroplasty (TKA) in adults undergoing a TKA procedure at Houston Methodist Hospital. The main questions it aims to answer are: Does IO administration of vancomycin and cefazolin protect against perioperative exposure risks? Is there a difference in post-operative complication rates between IV and IO administration of these drugs? Participants will be randomized to receive either the standard of care IV administration of Vancomycin and Cefazolin, or the IO administration of Vancomycin and Cefazolin.

Sponsor: The Methodist Hospital Research Institute

Who Can Participate

Inclusion Criteria

Patient is scheduled to undergo an elective primary total knee arthroplasty.
Patient is able to understand the study design and intervention and gives informed consent to participate in the study.
Patient is 18 years or older.

Exclusion Criteria

Contraindication to receiving vancomycin or cefazolin.
Body mass index (BMI) \> 40.
Uncontrolled Diabetes (defined as A1c \> 7.5%).
Patient received or is scheduled to receive IV vancomycin or cefazolin within 7 days prior to their planned procedure.
Any hardware, condition, or anatomic status that prevents the tibial tubercle from being a viable intraosseous injection site.
Refusal to participate
Any condition, in the opinion of the primary investigator, that deems the participant unsuitable for participation in the research study.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Houston?

Yes, this clinical trial (NCT06640491) has an active research site in Houston, TX that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Total Knee Arthroplasty Treatment Options in Houston, TX

If you're searching for total knee arthroplasty treatment options in Houston, TX, this clinical trial (NCT06640491) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Houston research site is actively enrolling participants for this phase 1/2 clinical trial. You'll receive care from experienced total knee arthroplasty specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all total knee arthroplasty clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Houston, TX