San Diego, CANCT07282782Now EnrollingIRB Ready

Total Knee Arthroplasty Clinical Trial in San Diego, CA

Access cutting-edge total knee arthroplasty treatment through this phase 4 clinical trial at a research site in San Diego. Study-provided care at no cost to qualified participants.

Sponsored by University of California, San Diego

Quick Self-Assessment

See if you qualify for this San Diego location

Preparing your pre-screening questions…

Expert Care in San Diego

Access total knee arthroplasty specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related total knee arthroplasty treatment provided free

Apply for This San Diego Location

Check if you qualify for this total knee arthroplasty clinical trial in San Diego, CA

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to San Diego

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit San Diego site if eligible
  4. 4Begin participation

About This Total Knee Arthroplasty Study in San Diego

Periprosthetic joint infection (PJI) is a national health crisis and leads to very poor outcomes for patients undergoing elective joint replacement. Within the realm of elective total knee arthroplasty (TKA), various methods of infection prophylaxis are in place. These include sterile precautions, would/tissue handling, and antibiotic prophylaxis. With respect to the latter, various approaches have been utilized including intravenous and intraosseous administration of vancomycin, preoperatively. Intraosseous administration does require another wound and a specific device to administer. The investigators proposed that intraarticular injection of vancomycin is non-inferior to intraosseous administration, thus reducing wounds, time, and cost.

Sponsor: University of California, San Diego

Who Can Participate

Inclusion Criteria

Any patient over the age of 18 years of age receiving treatment at UC San Diego Health
Undergoing primary unilateral TKA
Ability to provide consent

Exclusion Criteria

previous surgery on the knee (with the exception of arthroscopy)
contraindication to receiving vancomycin, cefepime or cefazolin (ie, allergy, etc)
diabetics with A1c\>7.5% (unless controlled fructosamine)
immunocompromised or immunosuppressed patients (HIV, Hepatitis C, end stage renal disease (ESRD), post transplant, chemotherapy or radiation therapy within 6 months of surgery, immunomodulating meducations)
no history of active infections
no history of chronic kidney disease

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in San Diego?

Yes, this clinical trial (NCT07282782) has an active research site in San Diego, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Total Knee Arthroplasty Treatment Options in San Diego, CA

If you're searching for total knee arthroplasty treatment options in San Diego, CA, this clinical trial (NCT07282782) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our San Diego research site is actively enrolling participants for this phase 4 clinical trial. You'll receive care from experienced total knee arthroplasty specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all total knee arthroplasty clinical trials near you to find additional studies recruiting in your area.

More Ankylosing Spondylitis Trials in San Diego, CA

See all ankylosing spondylitis clinical trials recruiting in San Diego — not just this study.

Browse Ankylosing Spondylitis Trials in San Diego →

Ready to Join in San Diego?

Take the first step toward participating in this groundbreaking clinical trial

Secure · Expert Care · San Diego, CA