Oak Brook, ILNCT05097976Now EnrollingIRB Ready

Total Knee Arthroplasty Clinical Trial in Oak Brook, IL

Access cutting-edge total knee arthroplasty treatment through this clinical trial at a research site in Oak Brook. Study-provided care at no cost to qualified participants.

Sponsored by Rush University Medical Center

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Expert Care in Oak Brook

Access total knee arthroplasty specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related total knee arthroplasty treatment provided free

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Check if you qualify for this total knee arthroplasty clinical trial in Oak Brook, IL

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Oak Brook

    Convenient for IL residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Oak Brook site if eligible
  4. 4Begin participation

About This Total Knee Arthroplasty Study in Oak Brook

The purpose of this study is to evaluate the efficacy of an oral methylprednisolone taper on acute postoperative pain, function, opioid consumption, nausea, and complications following outpatient total knee arthroplasty (TKA). We hypothesize that administration of an oral methylprednisolone taper starting on postoperative day 1 (POD 1) following TKA will be associated with improved pain and decreased opioid use, nausea, and complications at POD1-7, as compared to similar patients who receive placebo. Additionally, those taking methylprednisolone will report decreased pain and greater objective functional outcomes at 3 and 6 weeks postoperatively as compared to controls.

Sponsor: Rush University Medical Center

Who Can Participate

Inclusion Criteria

Any patient undergoing primary TKA with a diagnosis of osteoarthritis •≥ 18 years old
Willingness to undergo randomization

Exclusion Criteria

Reported chronic corticosteroid or opiate use
Suspected or confirmed periprosthetic joint infection
Revision TKA
Primary diagnosis other than osteoarthritis, including avascular necrosis, fracture, or post-traumatic arthritis
American Society of Anesthesiologists (ASA) score ≥ 4
Reported history of liver disease, renal disease, or diabetes mellitus
Current systemic fungal infection or other local infection
Immunocompromised or immunosuppressed
Current peptic ulcer disease
History of hypothyroidism, psychosis, heart failure, myasthenia gravis, ocular herpes simplex virus, or systemic sclerosis
Women with reported current pregnancy
Known hypersensitivity to methylprednisolone •≤ 18 years old
Inability to take oral medications
Unable to provide consent

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Oak Brook?

Yes, this clinical trial (NCT05097976) has an active research site in Oak Brook, IL that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Total Knee Arthroplasty Treatment Options in Oak Brook, IL

If you're searching for total knee arthroplasty treatment options in Oak Brook, IL, this clinical trial (NCT05097976) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Oak Brook research site is actively enrolling participants for this clinical trial. You'll receive care from experienced total knee arthroplasty specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all total knee arthroplasty clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Oak Brook, IL