Milwaukee, WINCT06871774Now EnrollingIRB Ready

Transcatheter Aortic Valve Replacement Clinical Trial in Milwaukee, WI

Access cutting-edge transcatheter aortic valve replacement treatment through this clinical trial at a research site in Milwaukee. Study-provided care at no cost to qualified participants.

Sponsored by Wake Forest University Health Sciences

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Expert Care in Milwaukee

Access transcatheter aortic valve replacement specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related transcatheter aortic valve replacement treatment provided free

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Check if you qualify for this transcatheter aortic valve replacement clinical trial in Milwaukee, WI

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Why Participate?

  • No-Cost Study Care

  • Local to Milwaukee

    Convenient for WI residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Milwaukee site if eligible
  4. 4Begin participation

About This Transcatheter Aortic Valve Replacement Study in Milwaukee

This study will compare the use of one Perclose device to the usual approach of two devices for pre-closure during Transcatheter Aortic Valve Replacement (TAVR). The study will compare the time it takes for bleeding to stop using the different closure approaches. The study will also compare complications when using one Perclose device versus two.

Sponsor: Wake Forest University Health Sciences

Who Can Participate

Inclusion Criteria

Patient age 18 or older
Transfemoral transcatheter aortic valve replacement (TAVR)
Implantation of CoreValve replacement valve
Access using 14 French sheaths
English speaking

Exclusion Criteria

Alternative Access Routes: Patients undergoing transcatheter aortic valve replacement (TAVR) via alternative access routes such as subclavian access or transapical access.
Planned Surgical Cut-Down: Patients planned for surgical cut-down procedures rather than percutaneous access.
Vascular Access Complications: Patients with known vascular complications at the femoral access site, such as residual hematoma, recent femoral arteriotomy or venotomy within the past 10 days, history of significant vascular complications or prior intravascular closure device use within the previous 30 days.
Arterial or Venous Issues: Patients with small femoral arteries or veins (\<5 mm in diameter), patients with access sites located in vascular grafts.
Body Composition: Patients with BMI \>35
Cardiac Vasculature: Patients with excess calcification of vessels as determined by echocardiography and/or CT angiography
Infection or Inflammation: Active systemic or cutaneous infection or inflammation in the vicinity of the groin.
Coagulation and Hematological Disorders: Known history of bleeding diathesis, coagulopathy, hypercoagulability, or platelet count \<100,000 cells/mm³. Pre-existing immunodeficiency disorder or chronic use of high-dose systemic steroids.
Severe Morbidity: Severe co-existing morbidities with a life expectancy less than 12 months.
Mobility Issues: Patients unable to routinely walk at least 20 feet without assistance.
Recent Anticoagulation: Use of low molecular weight heparin (LMWH) within 8 hours before or after the procedure.
Pregnancy and Lactation: Pregnant or lactating women.
Incompatible Procedure Plan: Patients receiving the Edwards Sapien valve (Edwards Lifesciences, Irvine, CA)
Contraindications: Patients with contraindications for the use of Perclose device.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Milwaukee?

Yes, this clinical trial (NCT06871774) has an active research site in Milwaukee, WI that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Transcatheter Aortic Valve Replacement Treatment Options in Milwaukee, WI

If you're searching for transcatheter aortic valve replacement treatment options in Milwaukee, WI, this clinical trial (NCT06871774) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Milwaukee research site is actively enrolling participants for this clinical trial. You'll receive care from experienced transcatheter aortic valve replacement specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all transcatheter aortic valve replacement clinical trials near you to find additional studies recruiting in your area.

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