Gainesville, FLNCT05616130Now EnrollingIRB Ready

Trauma Injury Clinical Trial in Gainesville, FL

Access cutting-edge trauma injury treatment through this clinical trial at a research site in Gainesville. Study-provided care at no cost to qualified participants.

Sponsored by University of Florida

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Expert Care in Gainesville

Access trauma injury specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related trauma injury treatment provided free

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Check if you qualify for this trauma injury clinical trial in Gainesville, FL

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Gainesville

    Convenient for FL residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Gainesville site if eligible
  4. 4Begin participation

About This Trauma Injury Study in Gainesville

The goal of this observational study is to better understand what happens to circulating blood after a patient experiences severe trauma injury. The main questions it aims to answer are: Is severe human trauma associated with specific patterns of development in the hematopoietic stem cells of these patients? and Does the initial severe trauma injury create immunosuppression and increase risk of in-hospital sepsis? Participants in study will give blood samples and a waste sample of bone marrow at time of operative repair of traumatic orthopedic injuries, supply medical information and participate in surveys and assessments during recovery from their injury(ies). Researchers will compare severe trauma injury patients to elective hip repair patients to see if immunosuppression and specific development patterns occur in the trauma patient versus the otherwise healthy hip surgery patient.

Sponsor: University of Florida

Who Can Participate

Inclusion Criteria

All adults age ≥ 18 years
Blunt and/or penetrating trauma resulting in long bone or pelvic fractures requiring open reduction internal fixation or closed reduction percutaneous pinning
Blunt and/or penetrating trauma patient with a. Injury Severity Score (ISS) greater than or equal to 25 b. ISS \> 15 and one of the following: i. \> 4 units of packed red blood cell or \>3 units of whole blood or \>1500 ml of autogenous blood product in the first 24 hours of admission ii. AIS (acute injury score) \> 2 spine iii. Shock on arrival (SBP \< 90) OR c. ISS \> 15 and two of the following: i. Age \> 55 ii. AIS \> 2 chest iii. +ethyl alcohol on arrival iv. Any red blood cell transfusion in first 24 hours

Exclusion Criteria

Patients not expected to survive greater than 48 hours.
Patients receiving chronic corticosteroids or immunosuppression therapies.
Previous bone marrow transplantation.
Patients with End Stage Renal Disease.
Patients with any pre-existing hematological disease.
Patients deemed to be futile care or have advanced directives limiting resuscitative efforts.
Patients with severe congestive heart failure (NY Heart Association Class IV).
Known HIV infection with CD4+ (clusters of differentiation) count \<200 cells/mm3
Chronic liver disease with MELD (Model for End-Stage Liver Disease) score ≥15 Elective Hip population Inclusion Criteria:
All adults (age ≥18)
Patient undergoing elective hip repair for non-infectious reasons.
Ability to obtain Informed Consent prior to operation. Exclusion Criteria:
Patients receiving chronic corticosteroids or immunosuppression therapies.
Pre-existing conditions such as pathological fractures, cancer, history of HIV, or history of connective tissue disease.
Previous bone marrow transplantation.
Patients with End Stage Renal Disease.
Patients with any pre-existing hematological disease.
Patients with known active/symptomatic COVID-19 (Coronavirus disease).

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Gainesville?

Yes, this clinical trial (NCT05616130) has an active research site in Gainesville, FL that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Trauma Injury Treatment Options in Gainesville, FL

If you're searching for trauma injury treatment options in Gainesville, FL, this clinical trial (NCT05616130) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Gainesville research site is actively enrolling participants for this clinical trial. You'll receive care from experienced trauma injury specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all trauma injury clinical trials near you to find additional studies recruiting in your area.

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