Dallas, TXNCT06480838Now EnrollingIRB Ready

Traumatic Brain Injury With Loss of Consciousness Clinical Trial in Dallas, TX

Access cutting-edge traumatic brain injury with loss of consciousness treatment through this clinical trial at a research site in Dallas. Study-provided care at no cost to qualified participants.

Sponsored by University of Texas Southwestern Medical Center

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Expert Care in Dallas

Access traumatic brain injury with loss of consciousness specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related traumatic brain injury with loss of consciousness treatment provided free

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Check if you qualify for this traumatic brain injury with loss of consciousness clinical trial in Dallas, TX

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Why Participate?

  • No-Cost Study Care

  • Local to Dallas

    Convenient for TX residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Dallas site if eligible
  4. 4Begin participation

About This Traumatic Brain Injury With Loss of Consciousness Study in Dallas

Cognitive impairment after moderate to severe traumatic brain injury (msTBI) not only significantly affects the quality of life in individuals with msTBI, but also increases the possibility of late-life dementia. The goal of this study is to determine whether acute (\< 1 week) cerebrovascular injury and its recovery within the first year postinjury measured by cerebral autoregulation and brain perfusion are associated with cognitive outcome at 12 months after msTBI. The results from this study will improve our understanding of cerebrovascular contributions to cognitive decline related to TBI and provide critical data to inform the development of strategies based on vascular mechanisms to improve cognition and prevent neurodegeneration after msTBI.

Sponsor: University of Texas Southwestern Medical Center

Who Can Participate

Inclusion Criteria

Documented/Verified TBI (ACRM Criteria) (eg, motor vehicle (MV) occupant, MV pedestrian/cyclist, fall, other non-intentional, violence/assault)
A documented moderate to severe TBI defined as: Glasgow Coma Scale (GCS) \< 13, or loss of consciousness (LOC) \> 30 minutes, or posttraumatic amnesia (PTA) \> 24 hours or intracranial neuroimaging abnormalities
Between the age 18 - 80 year-old
≤ 1 week postinjury
Acute brain CT for clinical care
Admitted to the hospital for TBI
Visual acuity/hearing adequate for testing
Fluent in English or Spanish
Patient or LAR ability to provide informed consent

Exclusion Criteria

Age greater or less than the range 18-80 years
Significant polytrauma that would interfere with follow-up and outcome assessment
Major debilitating baseline mental health disorders (e.g., schizophrenia, bipolar disorder, severe depression with active suicidal thoughts at the time of evaluation) that would interfere with follow-up and the validity of outcome assessment.
Major debilitating neurological disease (e.g., stroke, CVA, dementia, tumor) impairing baseline awareness, cognition, or validity of follow-up and outcome assessment.
Significant history of pre-existing conditions that would interfere with follow-up and outcome assessment (e.g., active substance abuse, alcoholism, HIV/AIDs, end-stage cancers, learning disabilities, developmental disorders)
Patients on psychiatric hold
Prisoners or patients in custody
Pregnancy in female subjects
Low likelihood of follow-up (e.g., participants or family indicating low interest, residence in another state or country, homeless or lack of reliable contacts)
Current participant in an interventional trial (e.g., drug, device, behavioral)
Penetrating TBI
Spinal cord injury with ASIA score of C or worse
Contraindications to MRI

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Dallas?

Yes, this clinical trial (NCT06480838) has an active research site in Dallas, TX that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Traumatic Brain Injury With Loss of Consciousness Treatment Options in Dallas, TX

If you're searching for traumatic brain injury with loss of consciousness treatment options in Dallas, TX, this clinical trial (NCT06480838) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Dallas research site is actively enrolling participants for this clinical trial. You'll receive care from experienced traumatic brain injury with loss of consciousness specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all traumatic brain injury with loss of consciousness clinical trials near you to find additional studies recruiting in your area.

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