San Diego, CANCT07616206Now EnrollingIRB Ready

Type 1 Diabetes (T1D) Clinical Trial in San Diego, CA

Access cutting-edge type 1 diabetes (t1d) treatment through this phase 2 clinical trial at a research site in San Diego. Study-provided care at no cost to qualified participants.

Sponsored by vTv Therapeutics

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Expert Care in San Diego

Access type 1 diabetes (t1d) specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related type 1 diabetes (t1d) treatment provided free

Apply for This San Diego Location

Check if you qualify for this type 1 diabetes (t1d) clinical trial in San Diego, CA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to San Diego

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit San Diego site if eligible
  4. 4Begin participation

About This Type 1 Diabetes (T1D) Study in San Diego

TTP399-206 is a Phase 2a multicenter double blind cross over randomized study of cadisegliatin in participants with T1D using hybrid closed loop systems to manage their diabetes. Participants using a hybrid closed loop insulin pump to manage their diabetes will be randomized to either receive blinded cadisegliatin 800 mg QD as an adjunctive therapy to their insulin treatment or placebo QD along with their insulin treatment. The trial begins with a screening period of up to 2 weeks, followed by a device training and insulin adjustment period of 1-2 weeks leading into the first double-blind treatment period of 6 weeks. There will then be a washout period of 2 weeks followed by the second double-blind treatment period of 6 weeks where the participants will cross-over to the treatment that they did not receive in the first treatment period.

Sponsor: vTv Therapeutics

Who Can Participate

Inclusion Criteria

Participants \>= 18 years of age
Fasting C-peptide levels \<0.6 ng/ml
Average TIR \< 70% recorded on their personal CGM data collected over the past 7 days prior to Visit 1
Currently on a hybrid closed loop device for at least 3 months and willing to stay on the same model of pump device for study duration
Willing to wear a study provided CGM for study duration
Total bilirubin ≤2×ULN, ALT and AST ≤3×ULN Key

Exclusion Criteria

Have Type 2 Diabetes Mellitus (DM), monogenic diabetes, maturity-onset diabetes, other unusual or rare forms of DM, or diabetes resulting from a secondary disease.
Have been hospitalized for DKA within 3 months
Have uncontrolled hypothyroidism or hyperthyroidism
Have QTcF interval \> 450 msec for males or \> 470 msec for females
Have a personal or family history of long QT syndrome, Torsades de pointes, or other complex ventricular arrhythmias
Have persistent, uncontrolled hypertension
Have clinically significant cardiovascular or cerebrovascular disease
Have proliferative retinopathy or maculopathy requiring acute treatment
Have a serious concomitant systemic disorder including but not limited to HIV or active Hep B or Hep C
Have been diagnosed and/or treated for malignancy within 3 years
Have used any of the following medications within the specified time periods: any non-insulin anti-diabetic therapies (e.g.SGLT-2 inhibitors, GLP-1 receptor agonists, metformin, sulfonylureas, DPP-4 inhibitors, pramlintide, a-glucosidase inhibitors, or glucose dependent insulinotropic polypeptide agonists) within 30 days, antipsychotic medications (e.g. olanzapine, risperidone, clozapine, quetiapine, and haloperidol) within 30 days, systemic corticosteroids for ≥7 days for a temporary medical condition within 30 days,

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in San Diego?

Yes, this clinical trial (NCT07616206) has an active research site in San Diego, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Type 1 Diabetes (T1D) Treatment Options in San Diego, CA

If you're searching for type 1 diabetes (t1d) treatment options in San Diego, CA, this clinical trial (NCT07616206) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our San Diego research site is actively enrolling participants for this phase 2 clinical trial. You'll receive care from experienced type 1 diabetes (t1d) specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all type 1 diabetes (t1d) clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · San Diego, CA