Tampa, FLNCT05666960Now EnrollingIRB Ready

Ulcerative Colitis Chronic Mild Clinical Trial in Tampa, FL

Access cutting-edge ulcerative colitis chronic mild treatment through this clinical trial at a research site in Tampa. Study-provided care at no cost to qualified participants.

Sponsored by Rise Therapeutics LLC

Quick Self-Assessment

See if you qualify for this Tampa location

Preparing your pre-screening questions…

Expert Care in Tampa

Access ulcerative colitis chronic mild specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related ulcerative colitis chronic mild treatment provided free

Apply for This Tampa Location

Check if you qualify for this ulcerative colitis chronic mild clinical trial in Tampa, FL

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Tampa

    Convenient for FL residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Tampa site if eligible
  4. 4Begin participation

About This Ulcerative Colitis Chronic Mild Study in Tampa

The goal of this study is to determine the safety and tolerability of orally taken probiotic (R-3750) in patients with mild to moderate ulcerative colitis. Patients will take an oral dosage of probiotic (R-3750) and provide patient-reported and physician scored measures of their colitis. Blood and fecal evaluations of inflammation and assessment of probiotic (R-3750) on fecal levels will also be measured.

Sponsor: Rise Therapeutics LLC

Who Can Participate

Inclusion Criteria

18-65 years of age
Ability to provide written informed consent
Confirmed diagnosed with UC by colonoscopy and histology and suffering from mild to moderate UC as defined by MMDAI with score of 3-9
On a stable dose of aminosalicylate (i.e. no change in medication within 4 weeks of study enrollment) and not planning to initiate new medication other than the study drug
For women of childbearing potential or men with a partner of childbearing potential, agree to use birth control methods (including hormonal contraceptives, intrauterine device (IUD) or hormone releasing system (IUS), vasectomy) and men will refrain from donating sperm during the study and at least 30 days after dosing (per FDA guidelines)
For the expansion cohort, a flexible sigmoidoscopy is required, unless an endoscopy was completed within 3 months from enrollment is available
Refrain from receiving any type of vaccinations during the study period (to include but not limited to influenza, COVID, shingles, tetanus, hepatitis, pneumonia, HPV, DPT, MMR, and polio)

Exclusion Criteria

Pregnancy, planned pregnancy, breastfeeding women
Evidence of severe UC disease (MMDAI score greater than or equal to 10)
Evidence of any active or recent infection including chronic infectious disease such as Hepatitis B, C, or HIV
Evidence of any active or recent chronic chest infection with bronchiectasis or sinusitis, or covid-19 infection in the past 3 months
Treatment with immunosuppressants or anti-cancer drugs, e.g., anti-TNF-α agents, anti-integrin agents, azathioprine or 6-MP, 6-thioguanine, methotrexate, ozanimod, tofacitinid, upadacitinib, tacrolimus, cyclophosphamide, or cyclosporine or any other therapy that is not an aminosalicylate within the last 3 months
Received an investigational drug within 3 months (or 5 half-lives, whichever is longer) before study entry
Use of steroidal drugs to treat UC (e.g., prednisone \>20 mg/day)
Use of probiotics within the last one (1) week and during the trial.
Treatment with systemic broad-spectrum antibiotics in the past 2 months
Major active systemic autoimmune disease other than UC
History of anaphylaxis or allergies to probiotics
History of alcohol or drug abuse within the past 2 years
History of stroke, or any cerebrovascular disease requiring medication/treatment
History of cancer, apart from successfully treated basal cell carcinoma or in situ carcinoma of the cervix \>1 year prior to enrollment
Significant laboratory abnormalities, including liver transaminases (AST or ALT) \> 1.5X the upper limit of normal.
Second degree or higher heart block or clinically significant arrythmia
Any other clinically significant renal, hepatic, hematological or other disease or laboratory abnormality which, in the opinion of the investigator, would interfere with the conduct, the interpretation of the safety signals or results of the trial, or would place the subject at unacceptable risk
Any condition or circumstance that, in the opinion of the Principal Investigator, would compromise the safety of the subject or the quality of study data

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Tampa?

Yes, this clinical trial (NCT05666960) has an active research site in Tampa, FL that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Ulcerative Colitis Chronic Mild Treatment Options in Tampa, FL

If you're searching for ulcerative colitis chronic mild treatment options in Tampa, FL, this clinical trial (NCT05666960) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Tampa research site is actively enrolling participants for this clinical trial. You'll receive care from experienced ulcerative colitis chronic mild specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all ulcerative colitis chronic mild clinical trials near you to find additional studies recruiting in your area.

More Heart Attack Trials in Tampa, FL

See all heart attack clinical trials recruiting in Tampa — not just this study.

Browse Heart Attack Trials in Tampa →

Browse More Trials by Condition

Heart Attack TrialsRheumatoid Arthritis TrialsUlcerative Colitis TrialsInflammatory Bowel Disease TrialsInterstitial Cystitis TrialsMyocardial Infarction TrialsInterstitial Lung Disease TrialsAll Conditions →

Ready to Join in Tampa?

Take the first step toward participating in this groundbreaking clinical trial

Secure · Expert Care · Tampa, FL