Los Angeles, CANCT07115862Now EnrollingIRB Ready

Ulcerative Colitis (Disorder) Clinical Trial in Los Angeles, CA

Access cutting-edge ulcerative colitis (disorder) treatment through this clinical trial at a research site in Los Angeles. Study-provided care at no cost to qualified participants.

Sponsored by University of California, Los Angeles

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Expert Care in Los Angeles

Access ulcerative colitis (disorder) specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related ulcerative colitis (disorder) treatment provided free

Apply for This Los Angeles Location

Check if you qualify for this ulcerative colitis (disorder) clinical trial in Los Angeles, CA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Los Angeles

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Los Angeles site if eligible
  4. 4Begin participation

About This Ulcerative Colitis (Disorder) Study in Los Angeles

The purpose of this study is to determine whether consumption of 237 ml of pomegranate juice daily for 8 weeks will: 1. lower inflammation (in the gut as well as generally in the body) and improve your overall quality of life 2. affect the microbes living in the gut (gut microbiota)

Sponsor: University of California, Los Angeles

Who Can Participate

Inclusion Criteria

• Adults ≥ 18 yo
Following a low-polyphenol and fiber diet (\< 3 servings of fruits/vegetables per day)
Mild-to-moderate UC at the time of screening (2 ≤ partial Mayo scores ≤ 5)
Supportive evidence of active inflammation (hsCRP \>1 mg/L, fecal calprotectin \>50 µg/g stool, or abnormal lower endoscopy) in individuals with biopsy-proven UC
Patients on 5-aminosalicylates must be on a stable dose for ≥ 4 weeks prior to screening
Patients on treatment with immunosuppressive therapy (e.g., azathioprine/6-mercaptopurine, methotrexate) must be on stable dose for 8 weeks prior to baseline visit
At the time of baseline visit, patients may be on no more than 20 mg/day of prednisone and 9 mg/day of budesonide MMX
Subjects must read and sign the Institutional Review Board-approved written informed consent prior to the initiation of any study specific procedures or enrollment. A subject will be excluded for any condition that might compromise the ability to give truly informed consent.

Exclusion Criteria

• Non-English speaker
Vegetarian/vegan
Known pomegranate allergy
Documented chronic disease besides UC, including diabetes, renal or liver diseases, metabolic syndrome, active cancer, MI or stroke, history of gastric bypass
Patients with CD, indeterminate/severe to fulminant colitis
History of colectomy or colonic dysplasia
Presence of ileal pouch or ostomy
Evidence of active bacterial or viral gastroenteritis as indicated by positive stool studies for ova \& parasites, Clostridium difficile, and stool culture
Recent hospitalizations (within 2 weeks of screening) for UC requiring IV steroids
Presence of the following labs indicative of severe colitis: a. Hemoglobin \< 8.0 g/dl b. Albumin \< 3.0 g/dl
Recent systemic antibiotics use (within 3 months of screening) or active use of anti-diarrheal medications
Taking supplements known to affect metabolism or gut microbiota composition (probiotics, fiber, etc.), unless willing to stop for the study duration
Use of Total Parenteral Nutrition (TPN)
Use of cyclosporine, tacrolimus, or thalidomide within 2 months prior to screening
Taking exogenous hormones (e.g., hormone replacement therapy)
Recent weight fluctuations (\>10% in the last 6 months)
Smoker or living with a smoker
Use of \>20 g of alcohol per day
Unable or unwilling to comply with the study protocol (including unwillingness to avoid watermelon and other lycopene-rich foods for the whole duration of the study)
Unable to provide consent

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Los Angeles?

Yes, this clinical trial (NCT07115862) has an active research site in Los Angeles, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Ulcerative Colitis (Disorder) Treatment Options in Los Angeles, CA

If you're searching for ulcerative colitis (disorder) treatment options in Los Angeles, CA, this clinical trial (NCT07115862) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Los Angeles research site is actively enrolling participants for this clinical trial. You'll receive care from experienced ulcerative colitis (disorder) specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all ulcerative colitis (disorder) clinical trials near you to find additional studies recruiting in your area.

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