Pittsburgh, PANCT04369560Now EnrollingIRB Ready

Urinary Bladder Neoplasms Clinical Trial in Pittsburgh, PA

Access cutting-edge urinary bladder neoplasms treatment through this clinical trial at a research site in Pittsburgh. Study-provided care at no cost to qualified participants.

Sponsored by Jodi Maranchie

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Expert Care in Pittsburgh

Access urinary bladder neoplasms specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related urinary bladder neoplasms treatment provided free

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Check if you qualify for this urinary bladder neoplasms clinical trial in Pittsburgh, PA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Pittsburgh

    Convenient for PA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Pittsburgh site if eligible
  4. 4Begin participation

About This Urinary Bladder Neoplasms Study in Pittsburgh

This is a phase Ib study of the safety and performance of a novel intravesical contrast-enhanced Magnetic Resonance Imaging protocol for determination of bladder cancer stage prior to transurethral resection of bladder tumor (21 subjects) or prior to radical cystectomy for muscle invasive disease (21 subjects). Subjects will undergo a single MRI study: a pre-contrast, single breath hold image followed by sterile placement of a temporary urethral catheter for instillation of a 50mL solution containing Gadobutrol (4 mM) plus ferumoxytol (5 mM) and then a second, post-contrast image. Images will be reviewed by two dedicated abdominal radiologists, who are blinded to the pathologic staging, for determination of tumor presence and depth of bladder wall penetration.

Sponsor: Jodi Maranchie

Who Can Participate

Inclusion Criteria

18 to 90 years of age
Able to understand and willing to sign a written informed consent document
A papillary tumor identified by cystoscopy that has been scheduled for TURBT OR histologically proven MIBC that is clinically localized and amenable to surgical resection with curative intent.
Performance status of ECOG 0 or 1
Normal renal function as defined as creatinine less than 1.5 x institutional upper limit of normal (ULN) OR creatinine clearance greater than or equal to 50 mL/min/1.73 m2 by Cockcroft-Gault formula for subjects with creatinine levels greater than or equal to 1.5 x ULN.

Exclusion Criteria

Severe hypersensitivity reaction to gadobutrol or ferumoxytol.
Severe claustrophobia that will prevent completion of the MRI study.
Any MRI-non-compatible implanted device, prosthetic or pacemaker.
Known or suspected metastatic disease.
Women with active pregnancy, lactation or plans to conceive
Untreated urinary tract infection
Known urethral stricture disease that would prohibit placement of foley catheter.
Any other conditions considered as unacceptable risk by the treating physician

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Pittsburgh?

Yes, this clinical trial (NCT04369560) has an active research site in Pittsburgh, PA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Urinary Bladder Neoplasms Treatment Options in Pittsburgh, PA

If you're searching for urinary bladder neoplasms treatment options in Pittsburgh, PA, this clinical trial (NCT04369560) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Pittsburgh research site is actively enrolling participants for this clinical trial. You'll receive care from experienced urinary bladder neoplasms specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all urinary bladder neoplasms clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Pittsburgh, PA