Hershey, PANCT03513770Now EnrollingIRB Ready

Venous Distension Reflex Clinical Trial in Hershey, PA

Access cutting-edge venous distension reflex treatment through this clinical trial at a research site in Hershey. Study-provided care at no cost to qualified participants.

Sponsored by Milton S. Hershey Medical Center

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Expert Care in Hershey

Access venous distension reflex specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related venous distension reflex treatment provided free

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Check if you qualify for this venous distension reflex clinical trial in Hershey, PA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Hershey

    Convenient for PA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Hershey site if eligible
  4. 4Begin participation

About This Venous Distension Reflex Study in Hershey

The study objective of this project is to examine the mechanisms of the venous distension reflex (VDR) in humans. We hypothesize that COX blockade with ketorolac tromethamine, an intravenous NSAID, will attenuate the muscle sympathetic nerve activity (MSNA) response to limb venous distension. To gain further insight into whether the COX byproducts directly stimulate chemically-sensitive afferents, or enable venodilation and indirectly evoke afferent stimulation, we will measure vein size using 3T MRI during venous distention with and without ketorolac infusions.

Sponsor: Milton S. Hershey Medical Center

Who Can Participate

Inclusion Criteria

Are capable of giving informed consent
Are any race or ethnicity
Are fluent in written and spoken English
Have a satisfactory history and physical exam to meet inclusion/

Exclusion Criteria

Are free of acute or chronic medical conditions
Are 21 - 35 years of age (inclusive)
Weigh over 50 kg Exclusion Criteria
Are less than 21 or over 35 years of age
Are Pregnant or nursing women
Are prisoners or institutionalized individuals or unable to consent
Any chronic diseases (hypertension, heart, lung, neuromuscular disease, kidney disease, diabetes or cancer).
Are taking medications that may affect their cardiovascular or nervous system
Has taken an NSAID within 48 hours of any visit (visit will need to be rescheduled)
Has never taken NSAIDs and therefore would not know if they are allergic to it
Have a supine BP \>140/90 mmHg
Have known allergy to ibuprofen-like drugs (NSAIDS) or aspirin
Have history of asthma or nasal polyps
Have history of GI bleeding or ulcers
Subjects with ferromagnetic metal implants
Subjects who are claustrophobic

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Hershey?

Yes, this clinical trial (NCT03513770) has an active research site in Hershey, PA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Venous Distension Reflex Treatment Options in Hershey, PA

If you're searching for venous distension reflex treatment options in Hershey, PA, this clinical trial (NCT03513770) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Hershey research site is actively enrolling participants for this clinical trial. You'll receive care from experienced venous distension reflex specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all venous distension reflex clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Hershey, PA