Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Chronic Spontaneous Urticaria Clinical Trials
Chronic Spontaneous Urticaria clinical trials are recruiting across 22 cities. Here are the cities with the most active studies:
Chronic Spontaneous Urticaria Trial Phases
4 research organizations are sponsoring chronic spontaneous urticaria trials.
About Chronic Spontaneous Urticaria
Chronic spontaneous urticaria involves the recurrence of hives and/or angioedema for more than six weeks without an identifiable external trigger. It significantly impacts quality of life. Treatment includes second-generation antihistamines and biologics like omalizumab.
Clinical trials are advancing new treatments for chronic spontaneous urticaria. Currently, 7 studies are recruiting a combined 4,937 participants across the United States. Research is being conducted by 4 organizations including Novartis Pharmaceuticals, Pfizer, The University of Texas Health Science Center at San Antonio and 1 others.
2026 Chronic Spontaneous Urticaria Research Landscape
As of August 2026, the chronic spontaneous urticaria clinical trial landscape includes 7 actively recruiting studies across 22 cities in the United States. These studies are collectively seeking 4,937 participants, with an average enrollment target of 705 per study.
The research spans multiple phases of development: 2 studies are in PHASE2, 1 study is in PHASE3, 1 study is in EARLY_PHASE1. The presence of Phase 3 trials indicates that some chronic spontaneous urticaria treatments are in late-stage testing and may be approaching regulatory review.
Research is being led by 4 different organizations, including Novartis Pharmaceuticals, Pfizer, The University of Texas Health Science Center at San Antonio, ARS Pharmaceuticals, Inc..
Geographically, chronic spontaneous urticaria trials are most concentrated in Kirksville, Missouri (2 trials); Phoenix, Arizona (2 trials); Little Rock, Arkansas (2 trials); Fountain Valley, California (2 trials); Birmingham, Alabama (1 trial) and 7 other cities.
Featured Chronic Spontaneous Urticaria Studies
Highlighted recruiting studies for chronic spontaneous urticaria, selected by enrollment size and research scope.
Remibrutinib in Real-world Clinical Practice
Prospective, multi-country, non-interventional study in patients with CSU where the treatment decision prior enrolment has been made to either escalate current sgH1-AHs treatment or escalate/switch current treatment to remibrutinib. The primary aim of this study is to gather real-world effectiveness and safety data for remibrutinib, a new treatment option, covering a broader, real-world clinical p...
Remibrutinib in Real-world Clinical Practice - a US Sub-study
Prospective, non-interventional study in patients with CSU where the treatment decision prior enrolment has been made to either escalate current sgH1-AHs treatment or escalate/switch current treatment to remibrutinib. The primary aim of this study is to gather real-world effectiveness and safety data for remibrutinib, a new treatment option, covering a broader, real-world clinical practice populat...
A Study to Evaluate Efficacy of Remibrutinib Compared to Dupilumab at Early Timepoints in Adults With Chronic Spontaneous Urticaria Inadequately Controlled by Second Generation H1-antihistamines
This is a US, multi-center, randomized, double-blind, double-dummy, Phase 3b study to evaluate efficacy of remibrutinib (25 mg twice daily \[b.i.d.\] by mouth \[p.o.\]) compared to dupilumab (600 mg loading dose administered subcutaneously (s.c.) followed by 300 mg every 2 weeks s.c.) at early timepoints (4 weeks and earlier), when administered as an add-on treatment to second generation H1-antihi...
Frequently Asked Questions About Chronic Spontaneous Urticaria Clinical Trials
Are there chronic spontaneous urticaria clinical trials near me?
Yes, there are 7 chronic spontaneous urticaria clinical trials currently recruiting across 22+ cities in the United States, including Kirksville, Missouri; Phoenix, Arizona; Little Rock, Arkansas. Browse the studies above to find one at a location convenient for you.
How do I join a chronic spontaneous urticaria clinical trial?
To join a chronic spontaneous urticaria clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are chronic spontaneous urticaria clinical trials free?
Yes, participation in chronic spontaneous urticaria clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of chronic spontaneous urticaria treatments are being studied?
Current chronic spontaneous urticaria clinical trials are testing a range of approaches across PHASE2 (2 studies), PHASE3 (1 study), EARLY_PHASE1 (1 study). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 4 research organizations.
Is it safe to participate in chronic spontaneous urticaria clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated August 28, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated August 28, 2026 · Data from ClinicalTrials.gov