PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes
PRECIDENTD is a randomized, open label, pragmatic clinical trial designed to compare rates of the total number of cardiovascular, kidney, and death events among two alternative treatments for patients...
Pentoxifylline in Diabetic Kidney Disease
Pentoxifylline (PTX) is a medication that has been on the market since 1984 for use in disease in the blood vessels of the legs. There is some preliminary information that it may protect the kidneys f...
Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease
Powerful new drugs that can prevent or delay end stage kidney disease (ESKD) - so called sodium-glucose cotransporter-2 inhibitors (SGLT2i) - are now available for patients with type 2 diabetes. Wheth...
Trial of Semaglutide for Diabetic Kidney Disease in Type 1 Diabetes
The primary objective of this study is to determine the effects of semaglutide on kidney oxygenation and function in type 1 diabetes. The secondary objective is to determine the glycemic effects and s...
Top Cities for Diabetic Kidney Disease Clinical Trials
Diabetic Kidney Disease clinical trials are recruiting across 30 cities. Here are the cities with the most active studies:
About Diabetic Kidney Disease
Diabetic kidney disease (diabetic nephropathy) is a complication of diabetes that affects the kidneys' filtering ability, potentially leading to kidney failure. It is the leading cause of end-stage kidney disease worldwide. Management includes blood sugar control, blood pressure medications, and SGLT2 inhibitors.
Clinical trials are advancing new treatments for diabetic kidney disease. Currently, 4 studies are recruiting a combined 8,720 participants across the United States. Research is being conducted by 4 organizations including Brigham and Women's Hospital, VA Office of Research and Development, Alessandro Doria and 1 others.
2026 Diabetic Kidney Disease Research Landscape
As of March 2026, the diabetic kidney disease clinical trial landscape includes 4 actively recruiting studies across 30 cities in the United States. These studies are collectively seeking 8,720 participants, with an average enrollment target of 2,180 per study.
Research is being led by 4 different organizations, including Brigham and Women's Hospital, VA Office of Research and Development, Alessandro Doria, University of Washington.
Geographically, diabetic kidney disease trials are most concentrated in Aurora, Colorado (3 trials); Baltimore, Maryland (1 trial); Duluth, Minnesota (1 trial); Columbia, Missouri (1 trial); New York, New York (1 trial) and 7 other cities.
Featured Diabetic Kidney Disease Studies
Highlighted recruiting studies for diabetic kidney disease, selected by enrollment size and research scope.
PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes
PRECIDENTD is a randomized, open label, pragmatic clinical trial designed to compare rates of the total number of cardiovascular, kidney, and death events among two alternative treatments for patients with type 2 diabetes (T2D) and either established atherosclerotic cardiovascular disease (ASCVD) or at high risk for ASCVD. To accomplish this objective, we will randomly assign 6,000 patients with e...
Pentoxifylline in Diabetic Kidney Disease
Pentoxifylline (PTX) is a medication that has been on the market since 1984 for use in disease in the blood vessels of the legs. There is some preliminary information that it may protect the kidneys from damage due to diabetes and other diseases. "Pentoxifylline in Diabetic Kidney Disease" is a study to bee conducted in 40 VA hospitals across the nation to determine definitively whether or not PTX...
Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease
Powerful new drugs that can prevent or delay end stage kidney disease (ESKD) - so called sodium-glucose cotransporter-2 inhibitors (SGLT2i) - are now available for patients with type 2 diabetes. Whether these drugs have similar effects in patients with type 1 diabetes (T1D) remains unknown because of the few studies in this population, due to concerns about the increase in risk of diabetic ketoaci...
Frequently Asked Questions About Diabetic Kidney Disease Clinical Trials
Are there diabetic kidney disease clinical trials near me?
Yes, there are 4 diabetic kidney disease clinical trials currently recruiting across 30+ cities in the United States, including Aurora, Colorado; Baltimore, Maryland; Duluth, Minnesota. Browse the studies above to find one at a location convenient for you.
How do I join a diabetic kidney disease clinical trial?
To join a diabetic kidney disease clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are diabetic kidney disease clinical trials free?
Yes, participation in diabetic kidney disease clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of diabetic kidney disease treatments are being studied?
Current diabetic kidney disease clinical trials are testing a range of approaches. These include new drugs, combination therapies, medical devices, and other interventions sponsored by 4 research organizations.
Is it safe to participate in diabetic kidney disease clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated March 1, 2026 from ClinicalTrials.gov
About This Data
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated March 1, 2026 · Data from ClinicalTrials.gov