Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Kidney Stones Clinical Trials
Kidney Stones clinical trials are recruiting across 25 cities. Here are the cities with the most active studies:
Kidney Stones Trial Phases
15 research organizations are sponsoring kidney stones trials.
About Kidney Stones
Kidney stones are hard deposits of minerals and salts that form inside the kidneys and can cause severe pain when passing through the urinary tract. They affect about 10% of people at some point. Treatment includes pain management, increased fluid intake, and procedures to break up or remove stones.
Clinical trials are advancing new treatments for kidney stones. Currently, 21 studies are recruiting a combined 3,464 participants across the United States. Research is being conducted by 15 organizations including Children's Hospital of Philadelphia, Mayo Clinic, Ohio State University and 12 others.
2026 Kidney Stones Research Landscape
As of October 2026, the kidney stones clinical trial landscape includes 21 actively recruiting studies across 25 cities in the United States. These studies are collectively seeking 3,464 participants, with an average enrollment target of 165 per study.
The research spans multiple phases of development: 13 studies are in NA, 2 studies are in PHASE4, 2 studies are in EARLY_PHASE1, 1 study is in PHASE2. Early-phase studies suggest new therapeutic approaches are being explored for kidney stones.
Research is being led by 15 different organizations, including Children's Hospital of Philadelphia, Mayo Clinic, Ohio State University, University of Miami, University of Kansas Medical Center, and 10 others. The large number of sponsors reflects significant research interest and investment in kidney stones treatment advancement.
Geographically, kidney stones trials are most concentrated in New York, New York (5 trials); Birmingham, Alabama (4 trials); Chicago, Illinois (4 trials); Kansas City, Kansas (3 trials); Dallas, Texas (2 trials) and 7 other cities.
Featured Kidney Stones Studies
Highlighted recruiting studies for kidney stones, selected by enrollment size and research scope.
Observational Approach Versus Surgical Intervention for Stones
The aims of the Observational Approach versus Surgical Intervention for Asymptomatic Stone (OASIS) trial are: 1) to determine whether observation compared to upfront surgery results in less healthcare-related life disruption due to kidney stones among children and adults with asymptomatic kidney stones; 2) to identify the groups benefiting the most from each strategy; and 3) to determine the prefe...
Prospective Research Rare Kidney Stones (ProRKS)
The purpose of this study is to determine the natural history of the hereditary forms of nephrolithiasis and chronic kidney disease (CKD), primary hyperoxaluria (PH), cystinuria, Dent disease and adenine phosphoribosyltransferase deficiency (APRTd) and acquired enteric hyperoxaluria (EH). The investigator will measure blood and urinary markers of inflammation and determine relationship to the dise...
FANS vs CVAC for Medium to Large Stones
Improvements in ureteroscopes have led to improved stone free rates. Two new devices (FANS - Flexible and Navigable Suction) and the CVAC ureteroscope have never been compared head to head. This trial will compare these two new suction ureteroscope technologies against each other
Frequently Asked Questions About Kidney Stones Clinical Trials
Are there kidney stones clinical trials near me?
Yes, there are 21 kidney stones clinical trials currently recruiting across 25+ cities in the United States, including New York, New York; Birmingham, Alabama; Chicago, Illinois. Browse the studies above to find one at a location convenient for you.
How do I join a kidney stones clinical trial?
To join a kidney stones clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are kidney stones clinical trials free?
Yes, participation in kidney stones clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of kidney stones treatments are being studied?
Current kidney stones clinical trials are testing a range of approaches across NA (13 studies), PHASE4 (2 studies), EARLY_PHASE1 (2 studies), PHASE2 (1 study). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 15 research organizations.
Is it safe to participate in kidney stones clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated October 17, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated October 17, 2026 · Data from ClinicalTrials.gov