Beta-Agonist Versus OnabotulinumtoxinA Trial for Urgency Urinary Incontinence
The goal of this clinical trial is to compare treatment outcomes between an oral medication (beta agonist) versus onabotulinumtoxinA injections in women with urgency urinary incontinence (UUI). Parti...
Reduced-dose Botox for Urgency Incontinence Among Elder Females
The purpose of this study is to study the treatment of urgency urinary incontinence (UUI), specifically among women 70 years and older, by comparing reduced versus standard dose of onabotulinumtoxinA ...
TReating Incontinence for Underlying Mental and Physical Health
The TRIUMPH study is a randomized, double-blinded, 3-arm, parallel-group trial designed to compare the effects of anticholinergic bladder therapy versus a) beta-3-adrenergic agonist bladder therapy an...
The Impact of Retropubic Lidocaine vs Saline on Postoperative Urinary Retention Following Midurethral Sling
Stress urinary incontinence affects millions of women worldwide and has a profound impact on the quality of life of older individuals, their subjective health status, levels of depression and need for...
Sildenafil for Treatment of Urinary Incontinence in Patients With Spinal Cord Injuries
The goal of this study is to determine whether administration of sildenafil will decrease urine leakage in patients with spinal cord injuries....
Top Cities for Urinary Incontinence Clinical Trials
Urinary Incontinence clinical trials are recruiting across 17 cities. Here are the cities with the most active studies:
About Urinary Incontinence
Urinary incontinence is the involuntary loss of urine, ranging from occasional leaking to complete inability to control the bladder. Types include stress, urge, overflow, and functional incontinence. Treatment includes pelvic floor exercises, medications, devices, and surgery.
Clinical trials are advancing new treatments for urinary incontinence. Currently, 5 studies are recruiting a combined 1,252 participants across the United States. Research is being conducted by 5 organizations including Women and Infants Hospital of Rhode Island, Dartmouth-Hitchcock Medical Center, University of California, San Francisco and 2 others.
2026 Urinary Incontinence Research Landscape
As of March 2026, the urinary incontinence clinical trial landscape includes 5 actively recruiting studies across 17 cities in the United States. These studies are collectively seeking 1,252 participants, with an average enrollment target of 250 per study.
Research is being led by 5 different organizations, including Women and Infants Hospital of Rhode Island, Dartmouth-Hitchcock Medical Center, University of California, San Francisco, West Penn Allegheny Health System, The University of Texas Medical Branch, Galveston.
Geographically, urinary incontinence trials are most concentrated in Birmingham, Alabama (2 trials); San Diego, California (2 trials); Pittsburgh, Pennsylvania (2 trials); Washington D.C., District of Columbia (1 trial); Albuquerque, New Mexico (1 trial) and 7 other cities.
Featured Urinary Incontinence Studies
Highlighted recruiting studies for urinary incontinence, selected by enrollment size and research scope.
Beta-Agonist Versus OnabotulinumtoxinA Trial for Urgency Urinary Incontinence
The goal of this clinical trial is to compare treatment outcomes between an oral medication (beta agonist) versus onabotulinumtoxinA injections in women with urgency urinary incontinence (UUI). Participants will be randomly selected to receive one of the two treatments. The primary outcome measure will be at 3 months, and women will be followed for a total of 12 months. Based on patient expert i...
Reduced-dose Botox for Urgency Incontinence Among Elder Females
The purpose of this study is to study the treatment of urgency urinary incontinence (UUI), specifically among women 70 years and older, by comparing reduced versus standard dose of onabotulinumtoxinA (BTX; trade name BOTOX(c)) injection in the bladder.
TReating Incontinence for Underlying Mental and Physical Health
The TRIUMPH study is a randomized, double-blinded, 3-arm, parallel-group trial designed to compare the effects of anticholinergic bladder therapy versus a) beta-3-adrenergic agonist bladder therapy and b) no bladder pharmacotherapy on cognitive, urinary, and other aging-related functional outcomes in ambulatory older women with urgency-predominant urinary incontinence and either normal or mildly i...
Frequently Asked Questions About Urinary Incontinence Clinical Trials
Are there urinary incontinence clinical trials near me?
Yes, there are 5 urinary incontinence clinical trials currently recruiting across 17+ cities in the United States, including Birmingham, Alabama; San Diego, California; Pittsburgh, Pennsylvania. Browse the studies above to find one at a location convenient for you.
How do I join a urinary incontinence clinical trial?
To join a urinary incontinence clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are urinary incontinence clinical trials free?
Yes, participation in urinary incontinence clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of urinary incontinence treatments are being studied?
Current urinary incontinence clinical trials are testing a range of approaches. These include new drugs, combination therapies, medical devices, and other interventions sponsored by 5 research organizations.
Is it safe to participate in urinary incontinence clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated March 1, 2026 from ClinicalTrials.gov
About This Data
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated March 1, 2026 · Data from ClinicalTrials.gov