Ann Arbor, MI7 Active Studies

Brain Cancer Clinical Trials in Ann Arbor, MI

Find 7 actively recruiting brain cancer clinical trials in Ann Arbor, MI. Connect with local research sites and explore new treatment options.

7
Active Trials
7
Sponsors
1,203
Enrolling

Recruiting Brain Cancer Studies in Ann Arbor

RecruitingAnn Arbor, MINCT06388733

A Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastoma

The goal of this Phase 3 clinical trial is to compare the efficacy of niraparib versus temozolomide (TMZ) in adult participants with newly-diagnosed, MGMT unmethylated glioblastoma multiforme (GBM). T...

450 participants
Ivy Brain Tumor Center
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RecruitingAnn Arbor, MINCT05009992

Combination Therapy for the Treatment of Diffuse Midline Gliomas

This phase II trial determines if the combination of ONC201 with different drugs, panobinostat or paxalisib, is effective for treating participants with diffuse midline gliomas (DMGs). Despite years o...

360 participants
University of California, San Francisco
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RecruitingAnn Arbor, MINCT04775485

A Study to Evaluate Tovorafenib in Pediatric and Young Adult Participants With Relapsed or Progressive Low-Grade Glioma and Advance Solid Tumors

This is a Phase 2, multi center, open-label study to evaluate the safety and efficacy of Type II RAF (tovorafenib) in pediatric participants with low-grade glioma or advanced solid tumors. Qualifying ...

141 participants
Day One Biopharmaceuticals, Inc.
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RecruitingAnn Arbor, MINCT05535166

Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed Medulloblastoma

This is a multi-center, multinational phase 2 trial that aims to explore the use of molecular and clinical risk-directed therapy in treatment of children 0-4.99 years of age with newly diagnosed medul...

120 participants
St. Jude Children's Research Hospital
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RecruitingAnn Arbor, MINCT06838676

ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas

This is a Phase II open-label study to investigate the safety and efficacy of ACT001 in patients with DIPG and H3K27-altered HGG....

60 participants
Nationwide Children's Hospital
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RecruitingAnn Arbor, MINCT04774718

A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Alectinib in Pediatric Participants With ALK Fusion-Positive Solid or CNS Tumors

This study will evaluate the safety, pharmacokinetics, and efficacy of alectinib in children and adolescents with ALK fusion-positive solid or CNS tumors for whom prior treatment has proven to be inef...

42 participants
Hoffmann-La Roche
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RecruitingAnn Arbor, MINCT06777433

Phase 2b Imaging Study of RAD101 in Participants With Suspected Recurrent Brain Metastases

This is an open-label, single dose, single arm, multicenter Phase 2b study to establish the imaging performance of RAD101 PET in participants who are ≥ 18 years of age and with suspected recurrent bra...

30 participants
Radiopharm Theranostics, Ltd
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About Brain Cancer Clinical Trials in Ann Arbor

Brain cancer includes tumors that originate in the brain (primary) or spread from other areas (metastatic). Glioblastoma (GBM) is the most common and aggressive primary brain tumor. Treatment typically combines surgery, radiation, and chemotherapy, with immunotherapy trials underway.

There are currently 7 brain cancer clinical trials recruiting participants in Ann Arbor, MI. These studies are seeking a combined 1,203 participants. Research is being sponsored by Ivy Brain Tumor Center, University of California, San Francisco, Day One Biopharmaceuticals, Inc. and 4 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Brain Cancer Clinical Trials in Ann Arbor — FAQ

Are there brain cancer clinical trials in Ann Arbor?

Yes, there are 7 brain cancer clinical trials currently recruiting in Ann Arbor, MI. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Ann Arbor?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Ann Arbor research site will contact you about next steps.

Are clinical trials in Ann Arbor free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Ann Arbor studies also compensate for your time and travel.

What brain cancer treatments are being tested?

The 7 active trials in Ann Arbor are testing new therapies including novel drugs, biologics, and treatment approaches for brain cancer.

Data updated March 2, 2026 from ClinicalTrials.gov