11 Pancreatic Cancer Clinical Trials in Baltimore, MD (2026)

Q: How do I join a clinical trial in Baltimore?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Baltimore research site will contact you.

Recruiting Pancreatic Cancer Studies in Baltimore

NCT06271291Recruiting

Pancreatic Cancer Detection Consortium (PCDC) Prospective Cohorts

This study evaluates individuals without pancreatic cancer, but who have been determined to be at higher-than-average lifetime risk of developing pancreatic cancer to help detect pancreatic cancer or ...

Baltimore, MD30,000 participantsMayo Clinic

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NCT02886247Recruiting

Pancreatic Cancer Registry: For Any Person With a Personal or Family History

The NFPTR was established in 1994 to find the causes of pancreatic cancer. In brief, the investigators are interested in both the genetic and non-genetic causes of pancreatic cancer. The investigators...

Baltimore, MD12,000 participantsJohns Hopkins University

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NCT02000089Recruiting

The Cancer of the Pancreas Screening-5 CAPS5)Study

Johns Hopkins clinical research office quality assurance group will monitor and audit this study at Johns Hopkins. The Sub Investigator at each site will be responsible for internal monitoring at thei...

Baltimore, MDPHASE39,000 participantsJohns Hopkins University

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NCT07491445Recruiting

Study of Daraxonrasib and Daraxonrasib + GnP as First-line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma

The purpose of this study is to evaluate the safety and efficacy of an investigational RAS(ON) inhibitor administered as monotherapy or in combination with chemotherapy, compared with standard of care...

Baltimore, MDPHASE3900 participantsRevolution Medicines, Inc.

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NCT07621718Recruiting

Study of Zoldonrasib + Chemo of Investigator's Choice vs Placebo + Chemo of Investigator's Choice as First-line Treatment in Metastatic KRAS G12D-mutated Pancreatic Adenocarcinoma ( RASolute 305 )

The purpose of this study is to evaluate the efficacy of an investigational RAS(ON) inhibitor administered in combination with chemotherapy compared to placebo in combination with chemotherapy....

Baltimore, MDPHASE3670 participantsRevolution Medicines, Inc.

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NCT02674100Recruiting

American Hepato-Pancreato-Biliary Association (AHPBA) Pancreatic Irreversible Electroporation (IRE) Registry

The purpose of this study is to create a registry to provide insight into treatment selection and treatment outcome of pancreatic IRE in order to develop an evidence base such that physicians can prov...

Baltimore, MD500 participantsUniversity of Louisville

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NCT07644559Recruiting

A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Pancreatic Cancer

This study will assess the safety and efficacy of VS-7375 alone and in combination with cetuximab in patients with metastatic KRAS G12D - mutated Pancreatic Cancer...

Baltimore, MDPHASE2180 participantsVerastem, Inc.

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NCT06782932Recruiting

Comparing Neoadjuvant/Adjuvant GVAX vs a mKRASvax Given With Anti-PD-1 and Anti-CD137 for Surgically Resectable Pancreatic Cancer

The purpose of this study is to determine the optimal dose of AGEN2373 that is safe when given in combination with balstilimab and Pancreatic GVAX Whole Cell Vaccine and evaluate the safety and clinic...

Baltimore, MDPHASE138 participantsSidney Kimmel Comprehensive Cancer Center at Johns Hopkins

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NCT05141513Recruiting

Intraoperative Radiation Therapy After Stereotactic Body Radiation Therapy and Chemotherapy in Treatment of Pancreatic Adenocarcinoma

This study is designed to investigate the safety of intraoperative radiation therapy (IORT) in patients with localized pancreatic cancer undergoing surgical resection after neoadjuvant chemotherapy an...

Baltimore, MDPHASE125 participantsSidney Kimmel Comprehensive Cancer Center at Johns Hopkins

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NCT03652428Recruiting

Phase I Nab-Paclitaxel Plus Gemcitabine With Proton Therapy for Locally Advanced Pancreatic Cancer (LAPC)

The purpose of this study is to determine the maximum tolerated dose of the chemotherapy drugs nab-paclitaxel and gemcitabine when combined with hypofractionated ablative proton therapy for the treatm...

Baltimore, MDPHASE124 participantsUniversity of Maryland, Baltimore

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NCT06941857Recruiting

NC410 and FOLFIRINOX in Combination With Nivolumab With or Without Ipilimumab in Patients With Untreated Metastatic Pancreatic Cancer

The purpose of this study is to evaluate safety of the treatment regimen and identify any novel toxicities....

Baltimore, MDPHASE220 participantsSidney Kimmel Comprehensive Cancer Center at Johns Hopkins

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About Pancreatic Cancer Clinical Trials in Baltimore

Pancreatic cancer begins in the tissues of the pancreas and is often diagnosed at an advanced stage. It is one of the most challenging cancers to treat. Clinical trials are actively investigating new approaches including immunotherapy and combination regimens.

There are currently 11 pancreatic cancer clinical trials recruiting participants in Baltimore, MD. These studies are seeking a combined 53,357 participants. Research is being sponsored by Mayo Clinic, Johns Hopkins University, Revolution Medicines, Inc. and 4 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Pancreatic Cancer Clinical Trials in Baltimore — FAQ

Are there pancreatic cancer clinical trials in Baltimore?

Yes, there are 11 pancreatic cancer clinical trials currently recruiting in Baltimore, MD. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Baltimore?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Baltimore research site will contact you about next steps.

Are clinical trials in Baltimore free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Baltimore studies also compensate for your time and travel.

What pancreatic cancer treatments are being tested?

The 11 active trials in Baltimore are testing new therapies including novel drugs, biologics, and treatment approaches for pancreatic cancer.

Data updated July 18, 2026 from ClinicalTrials.gov