24 Osteogenesis Imperfecta Clinical Trials in Bethesda, MD (2026)

Q: How do I join a clinical trial in Bethesda?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Bethesda research site will contact you.

Recruiting Osteogenesis Imperfecta Studies in Bethesda

NCT04969926Recruiting

Natural History Study of Parathyroid Disorders

Background: Parathyroid disorders are very common in the general population and include disorders of parathyroid excess, deficiency, or defects in parathyroid hormone (PTH) signaling. PTH, the main s...

Bethesda, MD3,000 participantsNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

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NCT00001160Recruiting

Studies on Tumors of the Thyroid

Participants in this study will be patients diagnosed with or suspected to have a thyroid nodule or thyroid cancer. The main purpose of this study is to further understand the methods for the diagnos...

Bethesda, MD2,500 participantsNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

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NCT00001159Recruiting

Natural History of Thyroid Function Disorders

Participants in this study will be patients diagnosed with or suspected to have a thyroid function disorder. These conditions may include: hypothyroidism, hyperthyroidism, thyroid hormone resistance, ...

Bethesda, MD2,500 participantsNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

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NCT00646022Recruiting

Natural History of Familial Carcinoid Tumor

This study will evaluate members in families with a history of small bowel carcinoid cancer to study the natural history of those family members that have the disease, determine ways to improve early ...

Bethesda, MD1,600 participantsNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

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NCT02523118Recruiting

OMEGA: Outcome Measures in Eosinophilic Gastrointestinal Disorders Across the Ages

The purpose of this observational study is to find the best measures to define how well a person with eosinophilic disorder is doing. People with EoE, EoG, EoN and EoC normally undergo endoscopy and/o...

Bethesda, MD1,350 participantsChildren's Hospital Medical Center, Cincinnati

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NCT07585266Recruiting

A Study to Investigate Velzatinib Compared With Imatinib in Adult Participants With Previously Untreated Metastatic and/or Unresectable Gastrointestinal Stromal Tumors (StrateGIST Frontline)

Gastrointestinal Stromal Tumour (GIST) is a soft tissue tumour that develops in the digestive system, most often in the stomach or small intestine. It is caused by changes in certain proteins that cau...

Bethesda, MDPHASE3800 participantsGlaxoSmithKline

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NCT07154823Recruiting

A Longitudinal Multi-Center Molecular Biomarker Discovery Registry for Patients With Hematologic Malignancies

The TEMPUS AQUARIUS Study is a non-interventional, longitudinal observational study focused on hematological malignancies. It will collect rich molecular (multi-omic) and clinical data from patient co...

Bethesda, MD550 participantsTempus AI

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NCT01109420Recruiting

Clinical and Genetic Studies in Familial Non-medullary Thyroid Cancer

Background: \- Researchers are studying types of thyroid cancer that seem to cluster in families. Non-medullary thyroid cancer accounts for the vast majority of all types of thyroid cancer, but littl...

Bethesda, MD500 participantsNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

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NCT02190266Recruiting

Pathogenesis and Genetics of Disseminated or Refractory Coccidioidomycosis

Background: \- Coccidioidomycosis is caused by a fungus that grows in the southwest United States and parts of Mexico and South America. This disease is caused by breathing dust containing the fungus...

Bethesda, MD400 participantsNational Institute of Allergy and Infectious Diseases (NIAID)

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NCT04102423Recruiting

CHIP/CCUS Natural History Protocol

Background: Clonal Hematopoiesis of Indeterminate Potential (CHIP) is a change in a person s DNA that can increase a person s risk of developing blood cancers or cardiovascular disease. CHIP occurs m...

Bethesda, MD306 participantsNational Heart, Lung, and Blood Institute (NHLBI)

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NCT03307304Recruiting

Investigations of Juvenile Neuronal Ceroid Lipofuscinosis

Background: CLN3, or Batten disease, is a genetic disorder. This deadly disease leads to decline of brain and nervous system functions. Symptoms of CLN3 typically occur between 4 and 7 years of age. ...

Bethesda, MD300 participantsEunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

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NCT06948110Recruiting

Deciphering the Genetic Architecture of Autoimmune Diseases

Background: Autoimmune diseases can be caused by genes people inherit from their parents. The gene changes that cause these diseases have been well studied in people with European and Asian ancestors...

Bethesda, MD300 participantsNational Human Genome Research Institute (NHGRI)

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NCT05436418Recruiting

The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell Transplantation

Background: Blood cancers (such as leukemias or lymphomas) often do not respond to standard treatments. A transplant of blood stem cells from a healthy donor can help people with these cancers. Somet...

Bethesda, MDPHASE1260 participantsNational Cancer Institute (NCI)

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NCT07444723Recruiting

Accuracy of 18F-Fluorocholine PET/MR and NeuroEXPLORER PET/CT Imaging for Localization of Parathyroid Tumors

Background: People have 4 parathyroid glands near the thyroid gland in the neck. Surgery is needed to remove a parathyroid gland that is too large or has a tumor. These glands can be in different pla...

Bethesda, MDPHASE2193 participantsNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

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NCT06275373Recruiting

The Effect of Teprotumumab on Thyroid Eye Disease and Thyroid Dysfunction

This protocol studies the clinical outcome of patients with active thyroid disease with visually significant signs and symptoms of proptosis, pain, diplopiam lid/orbital edema, or lid/orbital erythema...

Bethesda, MD100 participantsWalter Reed National Military Medical Center

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NCT05398809Recruiting

Evaluate the Efficacy and Safety of Ruxolitinib on Hair Regrowth in Patients With Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy (APECED)-Associated Alopecia Areata

Background: Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED) is a problem of the immune system. In people with APECED, the immune system makes a mistake and attacks the body. S...

Bethesda, MDPHASE270 participantsNational Institute of Allergy and Infectious Diseases (NIAID)

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NCT04927416Recruiting

The Role of 68-Gallium-DOTATATE-PET/CT in the Imaging of Metastatic Thyroid Cancer

Background: About 5% to 10% of differentiated thyroid cancers become resistant to standard treatment with radioactive iodine. In these cases, treatment options are limited and generally not effective...

Bethesda, MDPHASE254 participantsNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

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NCT06310239Recruiting

Microbiome Population Adaptation Study

The investigators will accomplish our research aims by collecting cutaneous microbiome samples from 50 persons that have undergone the Osseointegration (OI) surgery at eight timepoints, prospectively....

Bethesda, MD50 participantsWalter Reed National Military Medical Center

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NCT06093867Recruiting

Early Detection of Infectious and Noninfectious Lung Diseases Following Allogeneic Hematopoietic Stem Cell Transplantation

Background: Stem cell transplants (called hematopoietic stem cell transplantation, or HSCT) are used to treat various diseases. But when the cells for this procedure are donated by someone other than...

Bethesda, MD40 participantsNational Heart, Lung, and Blood Institute (NHLBI)

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NCT04008368Recruiting

Repeat Peripheral Blood Stem Cell Transplantation for Patients With Sickle Cell Disease and Falling Donor Myeloid Chimerism Levels

Background: Sickle cell disease can often be treated with blood stem cell transplants. But for some people the disease returns. This study will give a second transplant to people whose disease has re...

Bethesda, MDPHASE132 participantsNational Heart, Lung, and Blood Institute (NHLBI)

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NCT07202598Recruiting

Randomized Stepped Wedge Study of Emapalumab in APECED Enteritis

Background: Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED), also known as Autoimmune polyendocrine syndrome type-1 (APS-1), is a disease that causes the immune system to atta...

Bethesda, MDPHASE230 participantsNational Institute of Allergy and Infectious Diseases (NIAID)

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NCT03841617Recruiting

The Use of 124-I-PET/CT Whole Body and Lesional Dosimetry in Differentiated Thyroid Cancer

Study rationale High risk patients with differentiated thyroid cancer (DTC) require therapy with 131 I under thyroid stimulating hormone (TSH) stimulation. There are two methods of TSH stimulation en...

Bethesda, MDPHASE230 participantsNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

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NCT06383091Recruiting

Impact of Manual Therapy on Laryngeal Function Following Total Thyroidectomy

In this clinical trial, the investigators are seeking to learn if a course of voice therapy, including neck massage, stretches and pain science education in addition to voice exercise and scar massage...

Bethesda, MDNA20 participantsJohns Hopkins University

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NCT06730126Recruiting

Study of the ITK Inhibitor Soquelitinib to Reduce Lymphoproliferation and Improve Cytopenias in Autoimmune Lymphoproliferative Syndrome (ALPS)-FAS Patients

Background: Autoimmune lymphoproliferative syndrome (ALPS) is a rare disorder of the immune system caused by a mutation in the FAS gene. In ALPS, the body stores too many germ-fighting cells called l...

Bethesda, MDPHASE215 participantsNational Institute of Allergy and Infectious Diseases (NIAID)

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About Osteogenesis Imperfecta Clinical Trials in Bethesda

Osteogenesis imperfecta is a group of genetic disorders mainly affecting the bones, causing them to break easily, often from little or no apparent cause. It is caused by defects in collagen production. Treatment includes bisphosphonates, physical therapy, and surgical rodding.

There are currently 24 osteogenesis imperfecta clinical trials recruiting participants in Bethesda, MD. These studies are seeking a combined 15,000 participants. Research is being sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Children's Hospital Medical Center, Cincinnati, GlaxoSmithKline and 8 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Osteogenesis Imperfecta Clinical Trials in Bethesda — FAQ

Are there osteogenesis imperfecta clinical trials in Bethesda?

Yes, there are 24 osteogenesis imperfecta clinical trials currently recruiting in Bethesda, MD. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Bethesda?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Bethesda research site will contact you about next steps.

Are clinical trials in Bethesda free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Bethesda studies also compensate for your time and travel.

What osteogenesis imperfecta treatments are being tested?

The 24 active trials in Bethesda are testing new therapies including novel drugs, biologics, and treatment approaches for osteogenesis imperfecta.

Data updated October 12, 2026 from ClinicalTrials.gov